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From affinity selection to kinetic selection in Germinal Centre modelling

Affinity maturation is an evolutionary process by which the affinity of antibodies (Abs) against specific antigens (Ags) increases through rounds of B-cell proliferation, somatic hypermutation, and positive selection in germinal centres (GC). The positive selection of B cells depends on affinity, bu...

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Detalles Bibliográficos
Autores principales:	Lashgari, Danial, Merino Tejero, Elena, Meyer-Hermann, Michael, Claireaux, Mathieu A. F., van Gils, Marit J., Hoefsloot, Huub C. J., van Kampen, Antoine H. C.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200358/ https://www.ncbi.nlm.nih.gov/pubmed/35658003 http://dx.doi.org/10.1371/journal.pcbi.1010168

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