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PRMT5 epigenetically regulates the E3 ubiquitin ligase ITCH to influence lipid accumulation during mycobacterial infection

Mycobacterium tuberculosis (Mtb), the causative agent of tuberculosis (TB), triggers enhanced accumulation of lipids to generate foamy macrophages (FMs). This process has been often attributed to the surge in the expression of lipid influx genes with a concomitant decrease in those involved in lipid...

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Detalles Bibliográficos
Autores principales:	Borbora, Salik Miskat, Rajmani, Raju S., Balaji, Kithiganahalli Narayanaswamy
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200362/ https://www.ncbi.nlm.nih.gov/pubmed/35658060 http://dx.doi.org/10.1371/journal.ppat.1010095

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