Cargando…
Utility of Homologous Recombination Deficiency Biomarkers Across Cancer Types
Homologous recombination DNA repair deficiency (HRD) is associated with sensitivity to platinum and poly (ADP-ribose) polymerase inhibitors in certain cancer types, including breast, ovarian, pancreatic, and prostate. In these cancers, BRCA1/2 alterations and genomic scar signatures are useful indic...
Autores principales: | Takamatsu, Shiro, Brown, J.B., Yamaguchi, Ken, Hamanishi, Junzo, Yamanoi, Koji, Takaya, Hisamitsu, Kaneyasu, Tomoko, Mori, Seiichi, Mandai, Masaki, Matsumura, Noriomi |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Wolters Kluwer Health
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200383/ https://www.ncbi.nlm.nih.gov/pubmed/35613413 http://dx.doi.org/10.1200/PO.22.00085 |
Ejemplares similares
-
Utility of Homologous Recombination Deficiency Biomarkers Across Cancer Types
por: Takamatsu, Shiro, et al.
Publicado: (2021) -
Homologous recombination deficiency status-based classification of high-grade serous ovarian carcinoma
por: Takaya, Hisamitsu, et al.
Publicado: (2020) -
Mutation burden-orthogonal tumor genomic subtypes delineate responses to immune checkpoint therapy
por: Takamatsu, Shiro, et al.
Publicado: (2022) -
Time-Dependent Changes in Risk of Progression During Use of Bevacizumab for Ovarian Cancer
por: Takamatsu, Shiro, et al.
Publicado: (2023) -
Peritoneal dissemination of high-grade serous ovarian cancer: pivotal roles of chromosomal instability and epigenetic dynamics
por: Konishi, Ikuo, et al.
Publicado: (2022)