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Negative Ultraselection of Patients With RAS/BRAF Wild-Type, Microsatellite-Stable Metastatic Colorectal Cancer Receiving Anti–EGFR-Based Therapy

Several uncommon genomic alterations beyond RAS and BRAFV600E mutations drive primary resistance to anti–epidermal growth factor receptors (EGFRs) in metastatic colorectal cancer (mCRC). Our PRESSING panel (including PIK3CA exon 20/AKT1/PTEN mutations, ERBB2/MET amplifications, gene fusions, and mic...

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Detalles Bibliográficos
Autores principales:	Randon, Giovanni, Maddalena, Giulia, Germani, Marco Maria, Pircher, Chiara Carlotta, Manca, Paolo, Bergamo, Francesca, Giordano, Mirella, Sposetti, Caterina, Montagna, Aldo, Vetere, Guglielmo, Zambelli, Luca, Rasola, Cosimo, Boccaccino, Alessandra, Pagani, Filippo, Ambrosini, Margherita, Massafra, Marco, Fontanini, Gabriella, Milione, Massimo, Fassan, Matteo, Cremolini, Chiara, Lonardi, Sara, Pietrantonio, Filippo
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Wolters Kluwer Health 2022
Materias:	Original Reports
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200389/ https://www.ncbi.nlm.nih.gov/pubmed/35544729 http://dx.doi.org/10.1200/PO.22.00037

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