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Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth

Aim  The aim of this article was to evaluate uterocervical angle (UCA) and cervical length (CL) measured at 16 to 24 weeks of gestation using transvaginal sonography (TVS) as predictors of spontaneous preterm birth. Methods  In this prospective study, TVS was performed in 159 primigravidas with a si...

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Autores principales: Singh, Pramod Kumar, Srivastava, Resham, Kumar, Ishan, Rai, Sangeeta, Pandey, Saurabh, Shukla, Ram C., Verma, Ashish
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Thieme Medical and Scientific Publishers Pvt. Ltd. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200462/
https://www.ncbi.nlm.nih.gov/pubmed/35722650
http://dx.doi.org/10.1055/s-0041-1741411
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author Singh, Pramod Kumar
Srivastava, Resham
Kumar, Ishan
Rai, Sangeeta
Pandey, Saurabh
Shukla, Ram C.
Verma, Ashish
author_facet Singh, Pramod Kumar
Srivastava, Resham
Kumar, Ishan
Rai, Sangeeta
Pandey, Saurabh
Shukla, Ram C.
Verma, Ashish
author_sort Singh, Pramod Kumar
collection PubMed
description Aim  The aim of this article was to evaluate uterocervical angle (UCA) and cervical length (CL) measured at 16 to 24 weeks of gestation using transvaginal sonography (TVS) as predictors of spontaneous preterm birth. Methods  In this prospective study, TVS was performed in 159 primigravidas with a singleton, uncomplicated pregnancy at 16 to 24 weeks of gestation to measure the anterior UCA and CL. All the cases were followed until labor to document gestational age at delivery. Results  The risk of spontaneous preterm birth was higher in women with obtuse UCA (>95 degrees) with sensitivity of 86.7%, specificity of 93.0%, positive predictive value of 83.0%, negative predictive value of 94.6%, and p -value of <0.001. The difference between the means was statistically significant ( p -value < 0.001). UCAs ≥105degrees and 95 to 105 degrees were found to be significantly associated with spontaneous preterm births at <34 weeks and 34 to 37 weeks, respectively. CL <2.5 cm was found to predict spontaneous preterm births at <37 weeks with sensitivity of 31.1%, specificity of 95.6%, and p -value of <0.001. UCA was found to be a better predictor of spontaneous preterm birth with a higher coefficient of variation (56.4%) when compared with CL (16.9%). Conclusions  UCA proved to be a novel ultrasound parameter that can serve as a better predictor of spontaneous preterm births in comparison to CL. A strong correlation exists between obtuse UCA and a risk of spontaneous preterm birth.
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spelling pubmed-92004622022-06-16 Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth Singh, Pramod Kumar Srivastava, Resham Kumar, Ishan Rai, Sangeeta Pandey, Saurabh Shukla, Ram C. Verma, Ashish Indian J Radiol Imaging Aim  The aim of this article was to evaluate uterocervical angle (UCA) and cervical length (CL) measured at 16 to 24 weeks of gestation using transvaginal sonography (TVS) as predictors of spontaneous preterm birth. Methods  In this prospective study, TVS was performed in 159 primigravidas with a singleton, uncomplicated pregnancy at 16 to 24 weeks of gestation to measure the anterior UCA and CL. All the cases were followed until labor to document gestational age at delivery. Results  The risk of spontaneous preterm birth was higher in women with obtuse UCA (>95 degrees) with sensitivity of 86.7%, specificity of 93.0%, positive predictive value of 83.0%, negative predictive value of 94.6%, and p -value of <0.001. The difference between the means was statistically significant ( p -value < 0.001). UCAs ≥105degrees and 95 to 105 degrees were found to be significantly associated with spontaneous preterm births at <34 weeks and 34 to 37 weeks, respectively. CL <2.5 cm was found to predict spontaneous preterm births at <37 weeks with sensitivity of 31.1%, specificity of 95.6%, and p -value of <0.001. UCA was found to be a better predictor of spontaneous preterm birth with a higher coefficient of variation (56.4%) when compared with CL (16.9%). Conclusions  UCA proved to be a novel ultrasound parameter that can serve as a better predictor of spontaneous preterm births in comparison to CL. A strong correlation exists between obtuse UCA and a risk of spontaneous preterm birth. Thieme Medical and Scientific Publishers Pvt. Ltd. 2022-02-28 /pmc/articles/PMC9200462/ /pubmed/35722650 http://dx.doi.org/10.1055/s-0041-1741411 Text en Indian Radiological Association. This is an open access article published by Thieme under the terms of the Creative Commons Attribution-NonDerivative-NonCommercial License, permitting copying and reproduction so long as the original work is given appropriate credit. Contents may not be used for commercial purposes, or adapted, remixed, transformed or built upon. ( https://creativecommons.org/licenses/by-nc-nd/4.0/ ) https://creativecommons.org/licenses/by-nc-nd/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution-NonCommercial-NoDerivatives License, which permits unrestricted reproduction and distribution, for non-commercial purposes only; and use and reproduction, but not distribution, of adapted material for non-commercial purposes only, provided the original work is properly cited.
spellingShingle Singh, Pramod Kumar
Srivastava, Resham
Kumar, Ishan
Rai, Sangeeta
Pandey, Saurabh
Shukla, Ram C.
Verma, Ashish
Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth
title Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth
title_full Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth
title_fullStr Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth
title_full_unstemmed Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth
title_short Evaluation of Uterocervical Angle and Cervical Length as Predictors of Spontaneous Preterm Birth
title_sort evaluation of uterocervical angle and cervical length as predictors of spontaneous preterm birth
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200462/
https://www.ncbi.nlm.nih.gov/pubmed/35722650
http://dx.doi.org/10.1055/s-0041-1741411
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