Cargando…

Integrating Network Pharmacology and Experimental Validation to Explore the Key Mechanism of Gubitong Recipe in the Treatment of Osteoarthritis

BACKGROUND: Gubitong Recipe (GBT) is a prescription based on the Traditional Chinese Medicine (TCM) theory of tonifying the kidney yang and strengthening the bone. A previous multicentral randomized clinical trial has shown that GBT can effectively relieve joint pain and improve quality of life with...

Descripción completa

Detalles Bibliográficos
Autores principales:	Chen, Guang-yao, Liu, Xiao-yu, Luo, Jing, Yu, Xin-bo, Liu, Yi, Tao, Qing-wen
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200584/ https://www.ncbi.nlm.nih.gov/pubmed/35720033 http://dx.doi.org/10.1155/2022/7858925

Ejemplares similares

Chondroprotective Effects of Gubitong Recipe via Inhibiting Excessive Mitophagy of Chondrocytes
por: Yu, Xin-bo, et al.
Publicado: (2022)

Prediction of Rhizoma Drynariae Targets in the Treatment of Osteoarthritis Based on Network Pharmacology and Experimental Verification
por: Chen, Guang-yao, et al.
Publicado: (2021)

Network Pharmacology Analysis and Experimental Validation to Investigate the Mechanism of Total Flavonoids of Rhizoma Drynariae in Treating Rheumatoid Arthritis
por: Chen, Guang-yao, et al.
Publicado: (2022)

Integrated network pharmacology and experimental validation to explore the mechanisms underlying naringenin treatment of chronic wounds
por: Sun, Rui, et al.
Publicado: (2023)

Integration of Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanisms of Zhuanggu Busui Formula Against Osteoporosis
por: Zhang, Huihao, et al.
Publicado: (2022)

Integrated bioinformatic analysis and experimental validation for exploring the key molecular of brain inflammaging
por: Du, Zhixin, et al.
Publicado: (2023)

Network Pharmacology-Based Strategy to Investigate the Mechanisms of Cibotium barometz in Treating Osteoarthritis
por: Chen, Guang-Yao, et al.
Publicado: (2022)

RecipeDB: a resource for exploring recipes
por: Batra, Devansh, et al.
Publicado: (2020)

Exploring the Mechanism of Resveratrol in Reducing the Soft Tissue Damage of Osteoarthritis Based on Network Pharmacology and Experimental Pharmacology
por: Long, Zhiyong, et al.
Publicado: (2021)

Exploring the Pharmacological Mechanisms of Xihuang Pills Against Prostate Cancer via Integrating Network Pharmacology and Experimental Validation In Vitro and In Vivo
por: Wu, Yongrong, et al.
Publicado: (2022)

Integrating network pharmacology and experimental verification to explore the pharmacological mechanisms of asparagus against polycystic ovary syndrome
por: Xing, Jinshan, et al.
Publicado: (2023)

Exploring the active mechanism of berberine against HCC by systematic pharmacology and experimental validation
por: Song, Lei, et al.
Publicado: (2019)

Integrating Network Pharmacology and Experimental Validation to Explore the Pharmacological Mechanism of Astragaloside IV in Treating Bleomycin-Induced Pulmonary Fibrosis
por: Yuan, Su, et al.
Publicado: (2023)

Network pharmacology integrated with experimental validation to explore the therapeutic role and potential mechanism of Epimedium for spinal cord injury
por: Fu, Xuanhao, et al.
Publicado: (2023)

Molecular mechanisms of the Guizhi decoction on osteoarthritis based on an integrated network pharmacology and RNA sequencing approach with experimental validation
por: Chen, Yan, et al.
Publicado: (2023)

Investigating the cardioprotective effects of Fuzheng Yangxin recipe based on network pharmacology and experimental evaluation
por: Wang, Anzhu, et al.
Publicado: (2022)

Exploring the pharmacological mechanisms of icaritin against nasopharyngeal carcinoma via network pharmacology and experimental validation
por: Liu, Minglu, et al.
Publicado: (2022)

Exploring the Mechanism of Dangguiliuhuang Decoction Against Hepatic Fibrosis by Network Pharmacology and Experimental Validation
por: Cao, Hui, et al.
Publicado: (2018)

A Study on the Potential Mechanism of Shujin Dingtong Recipe against Osteoarthritis Based on Network Pharmacology and Molecular Docking
por: Yuan, Zhen-zhen, et al.
Publicado: (2022)

Corrigendum: Network pharmacology integrated with experimental validation to explore the therapeutic role and potential mechanism of Epimedium for spinal cord injury
por: Fu, Xuanhao, et al.
Publicado: (2023)

Corrigendum: Exploring the pharmacological mechanisms of icaritin against nasopharyngeal carcinoma via network pharmacology and experimental validation
por: Liu, Minglu, et al.
Publicado: (2023)

Integrating network pharmacology and experimental validation to explore the effect and mechanism of AD-1 in the treatment of colorectal cancer
por: Li, Jiawei, et al.
Publicado: (2023)

Huoxue Qianyang Qutan Recipe Protects against Early Renal Damage Induced by Obesity-Related Hypertension via the SIRT1/NF-κB/IL-6 Pathway: Integrating Network Pharmacology and Experimental Validation-Based Strategy
por: Wang, Mingzhu, et al.
Publicado: (2022)

Integrated network pharmacology and experimental validation to explore the potential pharmacological mechanism of Qihuang Granule and its main ingredients in regulating ferroptosis in AMD
por: Wang, Lu, et al.
Publicado: (2023)

Mechanism of Yiqi Huoxue Huatan recipe in the treatment of coronary atherosclerotic disease through network pharmacology and experiments
por: Huang, Hong-Tao, et al.
Publicado: (2023)

Integrated Experimental Approach, Phytochemistry, and Network Pharmacology to Explore the Potential Mechanisms of Cinnamomi Ramulus for Rheumatoid Arthritis
por: Liu, Jia, et al.
Publicado: (2022)

YuNü-Jian attenuates diabetes-induced cardiomyopathy: integrating network pharmacology and experimental validation
por: Wang, Wei, et al.
Publicado: (2023)

Network Pharmacology and Experimental Verification Revealed the Mechanism of Yiqi Jianpi Recipe on Chronic Obstructive Pulmonary Disease
por: Chen, Ke, et al.
Publicado: (2022)

Network pharmacology analysis combined with experimental validation to explore the therapeutic mechanism of salidroside on intestine ischemia reperfusion
por: Chen, Feng, et al.
Publicado: (2023)

Deciphering the pharmacological mechanisms of Chaenomeles Fructus against rheumatoid arthritis by integrating network pharmacology and experimental validation
por: Sun, Mengjia, et al.
Publicado: (2022)

Validation of the Key Active Ingredients and Anti-Inflammatory and Analgesic Effects of Shenjin Huoxue Mixture Against Osteoarthritis by Integrating Network Pharmacology Approach and Thin-Layer Chromatography Analysis
por: Yu, Mei-Xiang, et al.
Publicado: (2020)

Integrating Network Pharmacology and Experimental Validation to Investigate the Mechanisms of Huazhuojiedu Decoction to Treat Chronic Atrophic Gastritis
por: Hao, Xinyu, et al.
Publicado: (2020)

Integrating Network Pharmacology and Experimental Verification to Explore the Pharmacological Mechanisms of Aloin Against Gastric Cancer
por: Gao, Jia, et al.
Publicado: (2022)

The nutriRECIPE-Index – development and validation of a nutrient-weighted index for the evaluation of recipes
por: Forner, Frank, et al.
Publicado: (2021)

Integrating network pharmacology and an experimental validation strategy elucidates the protective effect and mechanism of callicarpa nudiflora against neuroinflammation
por: Yang, Guodong, et al.
Publicado: (2022)

Exploring the Therapeutic Composition and Mechanism of Jiang-Suan-Chu-Bi Recipe on Gouty Arthritis Using an Integrated Approach Based on Chemical Profile, Network Pharmacology and Experimental Support Using Molecular Cell Biology
por: Xiao, Nan, et al.
Publicado: (2020)

Integrating Network Pharmacology, Molecular Docking, and Experimental Validation to Investigate the Mechanism of (−)-Guaiol Against Lung Adenocarcinoma
por: Zeng, Yaoying, et al.
Publicado: (2022)

Network Pharmacology and Experimental Validation to Explore the Molecular Mechanisms of Compound Huangbai Liquid for the Treatment of Acne
por: Di, Huifeng, et al.
Publicado: (2023)

Integrated Network Pharmacology Analysis and Experimental Validation to Investigate the Molecular Mechanism of Triptolide in the Treatment of Membranous Nephropathy
por: Zhang, Ping Na, et al.
Publicado: (2022)

Integrating systematic pharmacology-based strategy and experimental validation to explore mechanism of Tripterygium glycoside on cholangiocyte-related liver injury
por: Li, Yajing, et al.
Publicado: (2022)

Cannot write session to /tmp/vufind_sessions/sess_krdseatdj9t0pmt08kpcadgqf9