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Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians

It is of interest to document the correlation of myeloperoxidase (MPO) and Troponin T (TnT) in young Indian patients with myocardial infarction using epidemiological data. A study with 220 (110 case and 110 control) participants with Acute Coronary Syndrome (both males and females) was completed. Pa...

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Autores principales: Jaiswal, Anoop, Doctor, Beenu, Verma, Manish Kumar, Vamne, Amrita
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200606/
https://www.ncbi.nlm.nih.gov/pubmed/35815198
http://dx.doi.org/10.6026/97320630018066
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author Jaiswal, Anoop
Doctor, Beenu
Verma, Manish Kumar
Vamne, Amrita
author_facet Jaiswal, Anoop
Doctor, Beenu
Verma, Manish Kumar
Vamne, Amrita
author_sort Jaiswal, Anoop
collection PubMed
description It is of interest to document the correlation of myeloperoxidase (MPO) and Troponin T (TnT) in young Indian patients with myocardial infarction using epidemiological data. A study with 220 (110 case and 110 control) participants with Acute Coronary Syndrome (both males and females) was completed. Patients were identified using a pre-designed PROFORMA at the OPD and IPD of the Medicine Department at the Index Medical College & Hospital, Malwanchal University and Moti Lal Nehru Medical College and Swaroop Rani Nehru Hospital in India. MPO and TnT were measured using the Sandwich ELISA (Sandwich Enzyme linked immunosorbent Assay) kit. TnT (pg/ml) (Mean ± SD) were high in the case group than control 134.7 ± 8.57 vs 96.6 ± 2.82; F = 145.9; t = 44.3; p < 0.01). Moreover, MPO was 3-fold high in case group than control (157±30.1 and 42.4±14.82, respectively). The differences was found statistically significant (p<0.001). This suggests a link between TnT and MPO among young Indian patients with myocardial infarction.
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spelling pubmed-92006062022-07-07 Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians Jaiswal, Anoop Doctor, Beenu Verma, Manish Kumar Vamne, Amrita Bioinformation Research Article It is of interest to document the correlation of myeloperoxidase (MPO) and Troponin T (TnT) in young Indian patients with myocardial infarction using epidemiological data. A study with 220 (110 case and 110 control) participants with Acute Coronary Syndrome (both males and females) was completed. Patients were identified using a pre-designed PROFORMA at the OPD and IPD of the Medicine Department at the Index Medical College & Hospital, Malwanchal University and Moti Lal Nehru Medical College and Swaroop Rani Nehru Hospital in India. MPO and TnT were measured using the Sandwich ELISA (Sandwich Enzyme linked immunosorbent Assay) kit. TnT (pg/ml) (Mean ± SD) were high in the case group than control 134.7 ± 8.57 vs 96.6 ± 2.82; F = 145.9; t = 44.3; p < 0.01). Moreover, MPO was 3-fold high in case group than control (157±30.1 and 42.4±14.82, respectively). The differences was found statistically significant (p<0.001). This suggests a link between TnT and MPO among young Indian patients with myocardial infarction. Biomedical Informatics 2022-01-31 /pmc/articles/PMC9200606/ /pubmed/35815198 http://dx.doi.org/10.6026/97320630018066 Text en © 2022 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Jaiswal, Anoop
Doctor, Beenu
Verma, Manish Kumar
Vamne, Amrita
Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians
title Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians
title_full Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians
title_fullStr Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians
title_full_unstemmed Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians
title_short Myeloperoxidase and troponin T are linked with myocardial infarction among young Indians
title_sort myeloperoxidase and troponin t are linked with myocardial infarction among young indians
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200606/
https://www.ncbi.nlm.nih.gov/pubmed/35815198
http://dx.doi.org/10.6026/97320630018066
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