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Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats

Fluorosis is a metabolic disease that is endemic in nearly 25 countries with India being one of the most affected. It primarily affects the bone and the teeth. Moringa oleifera (MO) leaves are known to reduce the effect of fluorosis on various tissues. Therefore, it is of interest to document the ef...

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Autores principales: Pagadala, Pravallika, Vinutha Shankar, MS, Hemalatha, A, Shashidhar, KN
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Biomedical Informatics 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200611/
https://www.ncbi.nlm.nih.gov/pubmed/35815197
http://dx.doi.org/10.6026/97320630018014
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author Pagadala, Pravallika
Vinutha Shankar, MS
Hemalatha, A
Shashidhar, KN
author_facet Pagadala, Pravallika
Vinutha Shankar, MS
Hemalatha, A
Shashidhar, KN
author_sort Pagadala, Pravallika
collection PubMed
description Fluorosis is a metabolic disease that is endemic in nearly 25 countries with India being one of the most affected. It primarily affects the bone and the teeth. Moringa oleifera (MO) leaves are known to reduce the effect of fluorosis on various tissues. Therefore, it is of interest to document the effect of Moringa oleifera leaves on the hematological profile of fluorosis affected rats. Twenty four Sprague Dawley rats were housed two per cage in a room with 12 hours light and 12 hours dark cycle. The rats were allowed to adjust to the laboratory environment for about one to two weeks before the beginning of the study. This study reveals that MO leaves is effective in reducing the plasma fluoride content. It also helps in improving the Hb % and RBC count in fluorosis affected rats. Data shows that Moringa olifera leaves powder is effective in reducing the plasma fluoride content. It also helps in improving the Hemoglobin percentage & Red Blood Cell count in fluorosis affected rats.
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spelling pubmed-92006112022-07-07 Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats Pagadala, Pravallika Vinutha Shankar, MS Hemalatha, A Shashidhar, KN Bioinformation Research Article Fluorosis is a metabolic disease that is endemic in nearly 25 countries with India being one of the most affected. It primarily affects the bone and the teeth. Moringa oleifera (MO) leaves are known to reduce the effect of fluorosis on various tissues. Therefore, it is of interest to document the effect of Moringa oleifera leaves on the hematological profile of fluorosis affected rats. Twenty four Sprague Dawley rats were housed two per cage in a room with 12 hours light and 12 hours dark cycle. The rats were allowed to adjust to the laboratory environment for about one to two weeks before the beginning of the study. This study reveals that MO leaves is effective in reducing the plasma fluoride content. It also helps in improving the Hb % and RBC count in fluorosis affected rats. Data shows that Moringa olifera leaves powder is effective in reducing the plasma fluoride content. It also helps in improving the Hemoglobin percentage & Red Blood Cell count in fluorosis affected rats. Biomedical Informatics 2022-01-31 /pmc/articles/PMC9200611/ /pubmed/35815197 http://dx.doi.org/10.6026/97320630018014 Text en © 2022 Biomedical Informatics https://creativecommons.org/licenses/by/3.0/This is an Open Access article which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly credited. This is distributed under the terms of the Creative Commons Attribution License.
spellingShingle Research Article
Pagadala, Pravallika
Vinutha Shankar, MS
Hemalatha, A
Shashidhar, KN
Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats
title Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats
title_full Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats
title_fullStr Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats
title_full_unstemmed Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats
title_short Effect of Moringa oleifera leaves on hematological profile of fluorosis affected rats
title_sort effect of moringa oleifera leaves on hematological profile of fluorosis affected rats
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200611/
https://www.ncbi.nlm.nih.gov/pubmed/35815197
http://dx.doi.org/10.6026/97320630018014
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