Impact of busulfan pharmacokinetics on outcome in adult patients receiving an allogeneic hematopoietic cell transplantation

Busulfan (Bu) is widely used in conditioning regimens before allogeneic hematopoietic cell transplantation, with variable metabolism due to interindividual differences of pharmacokinetics (PK). The purpose of this study was to correlate pharmacokinetics and clinical outcomes. Lower-AUC, in range-AUC...

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Detalles Bibliográficos
Autores principales: Seydoux, Claire, Battegay, Raphael, Halter, Joerg, Heim, Dominik, Rentsch, Katharina M., Passweg, Jakob R., Medinger, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200635/
https://www.ncbi.nlm.nih.gov/pubmed/35361896
http://dx.doi.org/10.1038/s41409-022-01641-6

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