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Formulation of an ovarian cancer vaccine with the squalene-based AddaVax adjuvant inhibits the growth of murine epithelial ovarian carcinomas

PURPOSE: Epithelial ovarian carcinoma (EOC) is the most lethal of all human gynecologic malignancies. We previously reported that vaccination of female mice with the extracellular domain of anti-Müllerian hormone receptor II (AMHR2-ED) in complete Freund’s adjuvant (CFA) generates AMHR2-ED specific...

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Detalles Bibliográficos
Autores principales: Mazumder, Suparna, Swank, Valerie, Dvorina, Nina, Johnson, Justin M., Tuohy, Vincent K.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Korean Vaccine Society 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200654/
https://www.ncbi.nlm.nih.gov/pubmed/35799868
http://dx.doi.org/10.7774/cevr.2022.11.2.163