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Remote solid cancers rewire hepatic nitrogen metabolism via host nicotinamide-N-methyltransferase
Cancers disrupt host homeostasis in various manners but the identity of host factors underlying such disruption remains largely unknown. Here we show that nicotinamide-N-methyltransferase (NNMT) is a host factor that mediates metabolic dysfunction in the livers of cancer-bearing mice. Multiple solid...
Autores principales: | , , , , , , , , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200709/ https://www.ncbi.nlm.nih.gov/pubmed/35705545 http://dx.doi.org/10.1038/s41467-022-30926-z |