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Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease
To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyzed regard...
Autores principales: | , , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200716/ https://www.ncbi.nlm.nih.gov/pubmed/35705551 http://dx.doi.org/10.1038/s41598-022-13404-w |
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author | Kravchenko, Dmitrij Hart, Christopher Garbe, Stephan Luetkens, Julian A. Isaak, Alexander Mesropyan, Narine Vergnat, Mathieu Leyens, Judith Attenberger, Ulrike Kuetting, Daniel |
author_facet | Kravchenko, Dmitrij Hart, Christopher Garbe, Stephan Luetkens, Julian A. Isaak, Alexander Mesropyan, Narine Vergnat, Mathieu Leyens, Judith Attenberger, Ulrike Kuetting, Daniel |
author_sort | Kravchenko, Dmitrij |
collection | PubMed |
description | To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyzed regarding dose length product (DLP) and effective dose (ED) after undergoing cardiothoracic CT imaging. Scan parameters were adjusted on a dual source/detector CT (DSCT) to minimize radiation dose while maintaining adequate quality. Image acquisition was performed at 70% of the R–R interval. Dose reducing measures included prospective electrocardiogram gating, utilizing slow injection velocities and foregoing bolus tracking during contrast injection. Image quality was assessed for artefacts, vessel definition, and noise on a 5-point scale (1 non-diagnostic, 5 excellent). Series were scored on a 0-to-3-point scale regarding answered clinical questions (0 non-diagnostic, 3 all clinical questions could be answered). The median DLP was 5.2 mGy*cm (IQR 3.5–7.8) leading to a median ED of 0.20 mSv (IQR 0.14–0.30). On average the acquired images scored 13.3 ± 2.1 (SD) out of a maximum 15 points with an intraclass correlation coefficient (ICC) of 0.94. All acquired series were able to fully answer all clinical questions scoring maximum points (ICC 1.0). Dual source high pitch CT protocols combined with custom contrast agent injection protocols in pediatric patients with CHD delivered sufficiently high diagnostic imaging quality combined with low submilisievert radiation doses. Prospective high pitch imaging is a reliable method for depiction of cardiac anatomy even in very young pediatric CHD patients with elevated heart rates. |
format | Online Article Text |
id | pubmed-9200716 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Nature Publishing Group UK |
record_format | MEDLINE/PubMed |
spelling | pubmed-92007162022-06-17 Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease Kravchenko, Dmitrij Hart, Christopher Garbe, Stephan Luetkens, Julian A. Isaak, Alexander Mesropyan, Narine Vergnat, Mathieu Leyens, Judith Attenberger, Ulrike Kuetting, Daniel Sci Rep Article To explore the image quality and radiation dose of dual source high-pitch cardiac computed tomography with tailored contrast injection protocols for pediatric congenital heart disease patients (CHD). In total, 27 infants with CHD (median age 109 days [IQR 6–199]) were retrospectively analyzed regarding dose length product (DLP) and effective dose (ED) after undergoing cardiothoracic CT imaging. Scan parameters were adjusted on a dual source/detector CT (DSCT) to minimize radiation dose while maintaining adequate quality. Image acquisition was performed at 70% of the R–R interval. Dose reducing measures included prospective electrocardiogram gating, utilizing slow injection velocities and foregoing bolus tracking during contrast injection. Image quality was assessed for artefacts, vessel definition, and noise on a 5-point scale (1 non-diagnostic, 5 excellent). Series were scored on a 0-to-3-point scale regarding answered clinical questions (0 non-diagnostic, 3 all clinical questions could be answered). The median DLP was 5.2 mGy*cm (IQR 3.5–7.8) leading to a median ED of 0.20 mSv (IQR 0.14–0.30). On average the acquired images scored 13.3 ± 2.1 (SD) out of a maximum 15 points with an intraclass correlation coefficient (ICC) of 0.94. All acquired series were able to fully answer all clinical questions scoring maximum points (ICC 1.0). Dual source high pitch CT protocols combined with custom contrast agent injection protocols in pediatric patients with CHD delivered sufficiently high diagnostic imaging quality combined with low submilisievert radiation doses. Prospective high pitch imaging is a reliable method for depiction of cardiac anatomy even in very young pediatric CHD patients with elevated heart rates. Nature Publishing Group UK 2022-06-15 /pmc/articles/PMC9200716/ /pubmed/35705551 http://dx.doi.org/10.1038/s41598-022-13404-w Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Article Kravchenko, Dmitrij Hart, Christopher Garbe, Stephan Luetkens, Julian A. Isaak, Alexander Mesropyan, Narine Vergnat, Mathieu Leyens, Judith Attenberger, Ulrike Kuetting, Daniel Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
title | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
title_full | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
title_fullStr | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
title_full_unstemmed | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
title_short | Image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
title_sort | image quality and radiation dose of dual source high pitch computed tomography in pediatric congenital heart disease |
topic | Article |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200716/ https://www.ncbi.nlm.nih.gov/pubmed/35705551 http://dx.doi.org/10.1038/s41598-022-13404-w |
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