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Predisposition of HLA-DRB1*04:01/*15 heterozygous genotypes to Japanese mixed connective tissue disease
Mixed connective tissue disease (MCTD) is a rare systemic autoimmune disease characterized by the production of anti-U1 ribonucleoprotein antibodies and systemic symptoms similar to those of some other autoimmune diseases. HLA-DRB1 polymorphisms are important genetic risk factors for MCTD, but preci...
Autores principales: | Oka, Shomi, Higuchi, Takashi, Furukawa, Hiroshi, Shimada, Kota, Hashimoto, Atsushi, Komiya, Akiko, Matsui, Toshihiro, Fukui, Naoshi, Suematsu, Eiichi, Ohno, Shigeru, Kono, Hajime, Katayama, Masao, Nagaoka, Shouhei, Migita, Kiyoshi, Tohma, Shigeto |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200795/ https://www.ncbi.nlm.nih.gov/pubmed/35705662 http://dx.doi.org/10.1038/s41598-022-14116-x |
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