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Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia

PURPOSE: Visceral obesity rather than body mass index has been reported to be associated with a higher incidence of incisional hernias. The aim of this study was to examine the relationship between CT measured adipose tissue and muscle in primary and recurrent incisional hernia. METHODS: Patients wi...

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Autores principales: Qandeel, H., Chew, C., Young, D., O’Dwyer, P. J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer Paris 2021
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200868/
https://www.ncbi.nlm.nih.gov/pubmed/33886018
http://dx.doi.org/10.1007/s10029-021-02416-6
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author Qandeel, H.
Chew, C.
Young, D.
O’Dwyer, P. J.
author_facet Qandeel, H.
Chew, C.
Young, D.
O’Dwyer, P. J.
author_sort Qandeel, H.
collection PubMed
description PURPOSE: Visceral obesity rather than body mass index has been reported to be associated with a higher incidence of incisional hernias. The aim of this study was to examine the relationship between CT measured adipose tissue and muscle in primary and recurrent incisional hernia. METHODS: Patients with a ‘Primary’ or ‘Recurrent incisional hernia’ were obtained from a prospective cohort of patients who were being assessed for incisional hernia repair over a 2-year period. Computerised tomography (CT)-images were analysed using NIH Image-J software to quantify adipose tissue and skeletal muscle cross-sectional areas at the level of lumber vertebra 3/4 using standard Hounsfield units. To test inter-observer ‘absolute agreement’, each parameter was measured independently by two investigators and reliability analysis performed. RESULTS: Thirty-six patients were included in the study: 15 had a Primary while 21 had a Recurrent incisional hernia. Both groups had similar baseline characteristics. Reliability analysis for CT-measured areas showed very high interclass correlation coefficient (ICC) between observers. Patients in the recurrent group had significantly greater subcutaneous adipose tissue (SAT) [median = 321.9cm(2) vs 230.9cm(2), p = 0.04] and visceral adipose tissue (VAT) [median = 221.1cm(2) vs 146.8cm(2), p = 0.03] than those in the primary group. There was no difference in skeletal muscle areas for right [median = 2.8cm(2) vs 2.9cm(2)] and left [median = 3.7cm(2) vs 4.1cm(2)] rectus muscles between groups. CONCLUSION: Our study shows that patients with a recurrent incisional hernia have significantly more subcutaneous and visceral adipose tissue than those with a primary incisional hernia. Further studies in this area are required if we are to reduce the burden of recurrent hernia following repair of a primary incisional hernia.
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spelling pubmed-92008682022-06-17 Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia Qandeel, H. Chew, C. Young, D. O’Dwyer, P. J. Hernia Original Article PURPOSE: Visceral obesity rather than body mass index has been reported to be associated with a higher incidence of incisional hernias. The aim of this study was to examine the relationship between CT measured adipose tissue and muscle in primary and recurrent incisional hernia. METHODS: Patients with a ‘Primary’ or ‘Recurrent incisional hernia’ were obtained from a prospective cohort of patients who were being assessed for incisional hernia repair over a 2-year period. Computerised tomography (CT)-images were analysed using NIH Image-J software to quantify adipose tissue and skeletal muscle cross-sectional areas at the level of lumber vertebra 3/4 using standard Hounsfield units. To test inter-observer ‘absolute agreement’, each parameter was measured independently by two investigators and reliability analysis performed. RESULTS: Thirty-six patients were included in the study: 15 had a Primary while 21 had a Recurrent incisional hernia. Both groups had similar baseline characteristics. Reliability analysis for CT-measured areas showed very high interclass correlation coefficient (ICC) between observers. Patients in the recurrent group had significantly greater subcutaneous adipose tissue (SAT) [median = 321.9cm(2) vs 230.9cm(2), p = 0.04] and visceral adipose tissue (VAT) [median = 221.1cm(2) vs 146.8cm(2), p = 0.03] than those in the primary group. There was no difference in skeletal muscle areas for right [median = 2.8cm(2) vs 2.9cm(2)] and left [median = 3.7cm(2) vs 4.1cm(2)] rectus muscles between groups. CONCLUSION: Our study shows that patients with a recurrent incisional hernia have significantly more subcutaneous and visceral adipose tissue than those with a primary incisional hernia. Further studies in this area are required if we are to reduce the burden of recurrent hernia following repair of a primary incisional hernia. Springer Paris 2021-04-22 2022 /pmc/articles/PMC9200868/ /pubmed/33886018 http://dx.doi.org/10.1007/s10029-021-02416-6 Text en © The Author(s) 2021 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Original Article
Qandeel, H.
Chew, C.
Young, D.
O’Dwyer, P. J.
Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia
title Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia
title_full Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia
title_fullStr Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia
title_full_unstemmed Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia
title_short Subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia
title_sort subcutaneous and visceral adipose tissue in patients with primary and recurrent incisional hernia
topic Original Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200868/
https://www.ncbi.nlm.nih.gov/pubmed/33886018
http://dx.doi.org/10.1007/s10029-021-02416-6
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