Amelioration of high-fat diet (HFD) + CCl4 induced NASH/NAFLD in CF-1 mice by activation of SIRT-1 using cinnamoyl sulfonamide hydroxamate derivatives: in-silico molecular modelling and in-vivo prediction

Non-alcoholic fatty liver disease (NAFLD) is one of the major hepatic metabolic disorders that occurs because of the accumulation of lipids in hepatocytes in the form of free fatty acids (FFA) and triglycerides (TG) which become non-alcoholic steatohepatitis (NASH). NOTCH-1 receptors act as novel ta...

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Detalles Bibliográficos
Autores principales: Sodum, Nalini, Rao, Vanishree, Cheruku, Sri Pragnya, Kumar, Gautam, Sankhe, Runali, Kishore, Anoop, Kumar, Nitesh, Rao, C. Mallikarjuna
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Springer International Publishing 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9200928/
https://www.ncbi.nlm.nih.gov/pubmed/35720958
http://dx.doi.org/10.1007/s13205-022-03192-5

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