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CD5 Controls Gut Immunity by Shaping the Cytokine Profile of Intestinal T Cells

CD5 is constitutively expressed on all T cells and is a negative regulator of lymphocyte function. However, the full extent of CD5 function in immunity remains unclear. CD5 deficiency impacts thymic selection and extra-thymic regulatory T cell generation, yet CD5 knockout was reported to cause no im...

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Detalles Bibliográficos
Autores principales: Schuster, Cornelia, Kiaf, Badr, Hatzihristidis, Teri, Ruckdeschel, Anna, Nieves-Bonilla, Janice, Ishikawa, Yuki, Zhao, Bin, Zheng, Peilin, Love, Paul E., Kissler, Stephan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201032/
https://www.ncbi.nlm.nih.gov/pubmed/35720357
http://dx.doi.org/10.3389/fimmu.2022.906499