Genipin protects against mitochondrial damage of the retinal pigment epithelium under hyperglycemia through the AKT pathway mediated by the miR-4429/JAK2 signaling axis

BACKGROUND: To investigate the protective effect and mechanism of genipin (GE) on mitochondrial damage in retinal pigment epithelial (RPE) cells induced by high glucose. METHODS: Differential genes of GE in the treatment of diabetic retinopathy (DR) were screened by the Gene Expression Omnibus (GEO)...

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Detalles Bibliográficos
Autores principales: Xu, Wenshuang, Chen, Qingyou, Zhang, Xiaofeng, Zhao, Yue, Wu, Shuang, Yang, Chao, Liu, Yubao, Liang, Lijie, Jia, Di, Li, Chaojun, Fan, Li, Shi, Yan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201119/
https://www.ncbi.nlm.nih.gov/pubmed/35722358
http://dx.doi.org/10.21037/atm-22-2219

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