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miR-145-5p targets MMP2 to protect brain injury in hypertensive intracerebral hemorrhage via inactivation of the Wnt/β-catenin signaling pathway

BACKGROUND: Differences in microRNA (miRNA) expression after hypertensive intracerebral hemorrhage (HICH) have been reported in human and animal models. miRNA-145 plays an important role in vascular endothelial cells. The purpose of this work was to determine the role of miR-145-5p in HICH and the m...

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Detalles Bibliográficos
Autores principales: Xiao, Wenfeng, Jiang, Zhengfang, Wan, Weifeng, Pan, Wen, Xu, Jianguo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201149/
https://www.ncbi.nlm.nih.gov/pubmed/35722425
http://dx.doi.org/10.21037/atm-22-1897