Deletion of the miR-144/451 cluster aggravates lethal sepsis-induced lung epithelial oxidative stress and apoptosis

BACKGROUND: Sepsis is associated with a high mortality rate. A major cause of death in sepsis patients is respiratory failure, which is characterized by oxidative injury, epithelial apoptosis, and increased lung permeability. MicroRNAs (miRs) are important regulators of sepsis progression. METHODS:...

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Detalles Bibliográficos
Autores principales: Wu, Fan, Yuan, Xiaoling, Liu, Weili, Meng, Lijun, Li, Xiuru, Gao, Xiang, Zhou, Shuting, Fang, Lei, Yu, Duonan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AME Publishing Company 2022
Materias:
Original Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201188/
https://www.ncbi.nlm.nih.gov/pubmed/35722395
http://dx.doi.org/10.21037/atm-22-1024

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