Single-cell profiling of the antigen-specific response to BNT162b2 SARS-CoV-2 RNA vaccine

RNA-based vaccines against SARS-CoV-2 have proven critical to limiting COVID-19 disease severity and spread. Cellular mechanisms driving antigen-specific responses to these vaccines, however, remain uncertain. Here we identify and characterize antigen-specific cells and antibody responses to the RNA...

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Detalles Bibliográficos
Autores principales: Kramer, Kevin J., Wilfong, Erin M., Voss, Kelsey, Barone, Sierra M., Shiakolas, Andrea R., Raju, Nagarajan, Roe, Caroline E., Suryadevara, Naveenchandra, Walker, Lauren M., Wall, Steven C., Paulo, Ariana, Schaefer, Samuel, Dahunsi, Debolanle, Westlake, Camille S., Crowe, James E., Carnahan, Robert H., Rathmell, Jeffrey C., Bonami, Rachel H., Georgiev, Ivelin S., Irish, Jonathan M.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201272/
https://www.ncbi.nlm.nih.gov/pubmed/35710908
http://dx.doi.org/10.1038/s41467-022-31142-5

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