A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma

Perivascular epithelioid cell tumors (PEComas) are related to the tuberous sclerosis complex (TSC) and are commonly benign. When malignant, they can be aggressive with local invasion and metastatic spread. Conventional PEComas do not have TFE3 gene rearrangement and are associated with TSC with a pr...

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Autores principales: Randhawa, Samender, Pinsker, Jessica, Amirapu, Madhurya, Sravanthi, Metlapalli Venkata, Ashok Kumar, Prashanth, Akhtar, Komal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: SAGE Publications 2022
Materias:
Case Report
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201293/
https://www.ncbi.nlm.nih.gov/pubmed/35699228
http://dx.doi.org/10.1177/23247096221103385
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author Randhawa, Samender
Pinsker, Jessica
Amirapu, Madhurya
Sravanthi, Metlapalli Venkata
Ashok Kumar, Prashanth
Akhtar, Komal
author_facet Randhawa, Samender
Pinsker, Jessica
Amirapu, Madhurya
Sravanthi, Metlapalli Venkata
Ashok Kumar, Prashanth
Akhtar, Komal
author_sort Randhawa, Samender
collection PubMed
description Perivascular epithelioid cell tumors (PEComas) are related to the tuberous sclerosis complex (TSC) and are commonly benign. When malignant, they can be aggressive with local invasion and metastatic spread. Conventional PEComas do not have TFE3 gene rearrangement and are associated with TSC with a preference for an occurrence at a younger age. We report a case of a young male who had progressive chronic hip pain and was found to have a TFE3-associated PEComa in his pelvic region.
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spelling pubmed-92012932022-06-17 A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma Randhawa, Samender Pinsker, Jessica Amirapu, Madhurya Sravanthi, Metlapalli Venkata Ashok Kumar, Prashanth Akhtar, Komal J Investig Med High Impact Case Rep Case Report Perivascular epithelioid cell tumors (PEComas) are related to the tuberous sclerosis complex (TSC) and are commonly benign. When malignant, they can be aggressive with local invasion and metastatic spread. Conventional PEComas do not have TFE3 gene rearrangement and are associated with TSC with a preference for an occurrence at a younger age. We report a case of a young male who had progressive chronic hip pain and was found to have a TFE3-associated PEComa in his pelvic region. SAGE Publications 2022-06-14 /pmc/articles/PMC9201293/ /pubmed/35699228 http://dx.doi.org/10.1177/23247096221103385 Text en © 2022 American Federation for Medical Research https://creativecommons.org/licenses/by/4.0/This article is distributed under the terms of the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/) which permits any use, reproduction and distribution of the work without further permission provided the original work is attributed as specified on the SAGE and Open Access pages (https://us.sagepub.com/en-us/nam/open-access-at-sage).
spellingShingle Case Report
Randhawa, Samender
Pinsker, Jessica
Amirapu, Madhurya
Sravanthi, Metlapalli Venkata
Ashok Kumar, Prashanth
Akhtar, Komal
A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma
title A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma
title_full A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma
title_fullStr A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma
title_full_unstemmed A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma
title_short A Rare Cause of Chronic Hip Pain From PEComa: An Aggressive Mesenchymal Sarcoma
title_sort rare cause of chronic hip pain from pecoma: an aggressive mesenchymal sarcoma
topic Case Report
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201293/
https://www.ncbi.nlm.nih.gov/pubmed/35699228
http://dx.doi.org/10.1177/23247096221103385
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