Alteration in Rab11‐mediated endocytic trafficking of LDL receptor contributes to angiotensin II‐induced cholesterol accumulation and injury in podocytes

OBJECTIVES: Exposure of podocytes to angiotensin II (Ang II) enhances the abundance of the cell surface glycoprotein, low‐density lipoprotein receptor (LDLR) and promotes significant changes in the cellular cholesterol content. Recent investigation provides evidence that the small GTPase Rab11 is in...

Descripción completa

Detalles Bibliográficos
Autores principales: Hu, Jijia, Zhu, Zijing, Chen, Zhaowei, Yang, Qian, Liang, Wei, Ding, Guohua
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201372/
https://www.ncbi.nlm.nih.gov/pubmed/35567428
http://dx.doi.org/10.1111/cpr.13229

Ejemplares similares

Ejemplares similares