The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine

UHPLC-HRMS (ultra-high-performance liquid chromatography-high resolution mass spectrometry) is a new technique that unifies the application of UHPLC with HRMS. Because of the high sensitivity and good separation ability of UHPLC and the sensitivity of HRMS, this technique has been widely used for st...

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Autores principales: Ma, Jieyao, Li, Kailin, Shi, Silin, Li, Jian, Tang, Sunv, Liu, LiangHong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201421/
https://www.ncbi.nlm.nih.gov/pubmed/35721122
http://dx.doi.org/10.3389/fphar.2022.922488
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author Ma, Jieyao
Li, Kailin
Shi, Silin
Li, Jian
Tang, Sunv
Liu, LiangHong
author_facet Ma, Jieyao
Li, Kailin
Shi, Silin
Li, Jian
Tang, Sunv
Liu, LiangHong
author_sort Ma, Jieyao
collection PubMed
description UHPLC-HRMS (ultra-high-performance liquid chromatography-high resolution mass spectrometry) is a new technique that unifies the application of UHPLC with HRMS. Because of the high sensitivity and good separation ability of UHPLC and the sensitivity of HRMS, this technique has been widely used for structure identification, quantitative determination, fingerprint analysis, and elucidation of the mechanisms of action of traditional Chinese medicines (TCMs) in recent years. This review mainly outlines the advantages of using UHPLC-HRMS and provides a survey of the research advances on UHPLC-HRMS for the quality control of TCMs.
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spelling pubmed-92014212022-06-17 The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine Ma, Jieyao Li, Kailin Shi, Silin Li, Jian Tang, Sunv Liu, LiangHong Front Pharmacol Pharmacology UHPLC-HRMS (ultra-high-performance liquid chromatography-high resolution mass spectrometry) is a new technique that unifies the application of UHPLC with HRMS. Because of the high sensitivity and good separation ability of UHPLC and the sensitivity of HRMS, this technique has been widely used for structure identification, quantitative determination, fingerprint analysis, and elucidation of the mechanisms of action of traditional Chinese medicines (TCMs) in recent years. This review mainly outlines the advantages of using UHPLC-HRMS and provides a survey of the research advances on UHPLC-HRMS for the quality control of TCMs. Frontiers Media S.A. 2022-06-02 /pmc/articles/PMC9201421/ /pubmed/35721122 http://dx.doi.org/10.3389/fphar.2022.922488 Text en Copyright © 2022 Ma, Li, Shi, Li, Tang and Liu. https://creativecommons.org/licenses/by/4.0/This is an open-access article distributed under the terms of the Creative Commons Attribution License (CC BY). The use, distribution or reproduction in other forums is permitted, provided the original author(s) and the copyright owner(s) are credited and that the original publication in this journal is cited, in accordance with accepted academic practice. No use, distribution or reproduction is permitted which does not comply with these terms.
spellingShingle Pharmacology
Ma, Jieyao
Li, Kailin
Shi, Silin
Li, Jian
Tang, Sunv
Liu, LiangHong
The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
title The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
title_full The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
title_fullStr The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
title_full_unstemmed The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
title_short The Application of UHPLC-HRMS for Quality Control of Traditional Chinese Medicine
title_sort application of uhplc-hrms for quality control of traditional chinese medicine
topic Pharmacology
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201421/
https://www.ncbi.nlm.nih.gov/pubmed/35721122
http://dx.doi.org/10.3389/fphar.2022.922488
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