A Pilot, Open-Label Study to Evaluate the Efficacy of Intra-Articular Administration of a Caninized TNF Receptor Fc Fusion Protein as a Treatment for Osteoarthritis-Associated Joint Pain

Tumor necrosis factor-α (TNF-α) is a potential target for osteoarthritis (OA) treatment. In several recent clinical studies in human OA, anti-TNF-α therapy showed promising results; however, these were open-label and based on patient-reported outcome measures. In this study, we developed a caninized...

Descripción completa

Detalles Bibliográficos
Autores principales: Nakanishi, Aoi, Lascelles, B. Duncan X., Allen, Julie, Case, Beth, Gearing, David, Enomoto, Masataka
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Veterinary Science
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201515/
https://www.ncbi.nlm.nih.gov/pubmed/35720854
http://dx.doi.org/10.3389/fvets.2022.836709

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201515/
https://www.ncbi.nlm.nih.gov/pubmed/35720854
http://dx.doi.org/10.3389/fvets.2022.836709

Ejemplares similares