The Effect of Serine Protease Inhibitors on Visceral Pain in Different Rodent Models With an Intestinal Insult

Background: Serine proteases are believed to play a key role in the origin of abdominal pain in IBD and IBS. We previously demonstrated a reduction of visceral pain in a post-inflammatory IBS rat model after a single intraperitoneal or intracolonic administration of a serine protease inhibitor. The...

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Detalles Bibliográficos
Autores principales: Ceuleers, Hannah, Hanning, Nikita, De bruyn, Michelle, De Man, Joris G, De Schepper, Heiko U, Li, Qian, Liu, Liansheng, Abrams, Steven, Smet, Annemieke, Joossens, Jurgen, Augustyns, Koen, De Meester, Ingrid, Pasricha, Pankaj J, De Winter, Benedicte Y
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201642/
https://www.ncbi.nlm.nih.gov/pubmed/35721192
http://dx.doi.org/10.3389/fphar.2022.765744

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