Synergic action of L-acetylcarnitine and L-methylfolate in Mouse Models of Stress-Related Disorders and Human iPSC-Derived Dopaminergic Neurons

The epigenetic agents, L-acetylcarnitine (LAC) and L-methylfolate (MF) are putative candidates as add-on drugs in depression. We evaluated the effect of a combined treatment with LAC and MF in two different paradigms of chronic stress in mice and in human inducible pluripotent stem cells (hiPSCs) di...

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Detalles Bibliográficos
Autores principales: Orlando, Rosamaria, Ginerete, Roxana Paula, Cavalleri, Laura, Aliperti, Vincenza, Imbriglio, Tiziana, Battaglia, Giuseppe, Zuena, Anna Rita, Nicoletti, Ferdinando, Merlo Pich, Emilio, Collo, Ginetta
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Pharmacology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201783/
https://www.ncbi.nlm.nih.gov/pubmed/35721218
http://dx.doi.org/10.3389/fphar.2022.913210

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201783/
https://www.ncbi.nlm.nih.gov/pubmed/35721218
http://dx.doi.org/10.3389/fphar.2022.913210

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