Internationalization of Read-Across as a Validated New Approach Method (NAM) for Regulatory Toxicology

Read-across (RAx) translates available information from well-characterized chemicals to a substance for which there is a toxicological data gap. The OECD is working on case studies to probe general applicability of RAx, and several regulations (e.g., EU-REACH) already allow this procedure to be used...

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Autores principales: Rovida, Costanza, Barton-Maclaren, Tara, Benfenati, Emilio, Caloni, Francesca, Chandrasekera, P. Charukeshi, Chesné, Christophe, Cronin, Mark T. D., De Knecht, Joop, Dietrich, Daniel R., Escher, Sylvia E., Fitzpatrick, Suzanne, Flannery, Brenna, Herzler, Matthias, Bennekou, Susanne Hougaard, Hubesch, Bruno, Kamp, Hennicke, Kisitu, Jaffar, Kleinstreuer, Nicole, Kovarich, Simona, Leist, Marcel, Maertens, Alexandra, Nugent, Kerry, Pallocca, Giorgia, Pastor, Manuel, Patlewicz, Grace, Pavan, Manuela, Presgrave, Octavio, Smirnova, Lena, Schwarz, Michael, Yamada, Takashi, Hartung, Thomas
Formato: Online Artículo Texto
Lenguaje:English
Publicado: 2020
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201788/
https://www.ncbi.nlm.nih.gov/pubmed/32369604
http://dx.doi.org/10.14573/altex.1912181

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