Ruxolitinib withdrawal complicating emergency aortic root replacement

Ruxolitinib, a Janus kinase inhibitor, is associated with severe withdrawal phenomena. Adequate tapering is often underemphasized in surgical emergencies and can complicate the postoperative course. We present a case of acute ruxolitinib withdrawal in a gentleman undergoing emergency cardiac surgery

Detalles Bibliográficos
Autores principales: Szpytma, Malgorzata (Maggie), Gimpel, Damian, Crouch, Gareth, Bennetts, Jayme S
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Oxford University Press 2022
Materias:
Vascular
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201970/
https://www.ncbi.nlm.nih.gov/pubmed/35640536
http://dx.doi.org/10.1093/icvts/ivac143
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author Szpytma, Malgorzata (Maggie)
Gimpel, Damian
Crouch, Gareth
Bennetts, Jayme S
author_facet Szpytma, Malgorzata (Maggie)
Gimpel, Damian
Crouch, Gareth
Bennetts, Jayme S
author_sort Szpytma, Malgorzata (Maggie)
collection PubMed
description Ruxolitinib, a Janus kinase inhibitor, is associated with severe withdrawal phenomena. Adequate tapering is often underemphasized in surgical emergencies and can complicate the postoperative course. We present a case of acute ruxolitinib withdrawal in a gentleman undergoing emergency cardiac surgery
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spelling pubmed-92019702022-06-16 Ruxolitinib withdrawal complicating emergency aortic root replacement Szpytma, Malgorzata (Maggie) Gimpel, Damian Crouch, Gareth Bennetts, Jayme S Interact Cardiovasc Thorac Surg Vascular Ruxolitinib, a Janus kinase inhibitor, is associated with severe withdrawal phenomena. Adequate tapering is often underemphasized in surgical emergencies and can complicate the postoperative course. We present a case of acute ruxolitinib withdrawal in a gentleman undergoing emergency cardiac surgery Oxford University Press 2022-05-30 /pmc/articles/PMC9201970/ /pubmed/35640536 http://dx.doi.org/10.1093/icvts/ivac143 Text en © The Author(s) 2022. Published by Oxford University Press on behalf of the European Association for Cardio-Thoracic Surgery. https://creativecommons.org/licenses/by-nc/4.0/This is an Open Access article distributed under the terms of the Creative Commons Attribution-NonCommercial License (https://creativecommons.org/licenses/by-nc/4.0/), which permits non-commercial re-use, distribution, and reproduction in any medium, provided the original work is properly cited. For commercial re-use, please contact journals.permissions@oup.com
spellingShingle Vascular
Szpytma, Malgorzata (Maggie)
Gimpel, Damian
Crouch, Gareth
Bennetts, Jayme S
Ruxolitinib withdrawal complicating emergency aortic root replacement
title Ruxolitinib withdrawal complicating emergency aortic root replacement
title_full Ruxolitinib withdrawal complicating emergency aortic root replacement
title_fullStr Ruxolitinib withdrawal complicating emergency aortic root replacement
title_full_unstemmed Ruxolitinib withdrawal complicating emergency aortic root replacement
title_short Ruxolitinib withdrawal complicating emergency aortic root replacement
title_sort ruxolitinib withdrawal complicating emergency aortic root replacement
topic Vascular
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9201970/
https://www.ncbi.nlm.nih.gov/pubmed/35640536
http://dx.doi.org/10.1093/icvts/ivac143
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