Toward the Total Synthesis of Alpkinidine: Michael Addition to Isoquinolinetrione CE Ring-System Synthons

[Image: see text] Strategies toward the total synthesis of the marine pyrroloacridine alkaloid alpkinidine have been explored, focusing on linking quinonoid CE ring-system synthons with the A ring, followed by condensation to form the B and D rings. The key Michael addition of the ester enolate deri...

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Detalles Bibliográficos
Autores principales: Buccini, Marco, Dhoro, Francis, Tham, Louisa, Skelton, Brian W., Williams, Craig M., Piggott, Matthew J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202020/
https://www.ncbi.nlm.nih.gov/pubmed/35722017
http://dx.doi.org/10.1021/acsomega.2c02117

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202020/
https://www.ncbi.nlm.nih.gov/pubmed/35722017
http://dx.doi.org/10.1021/acsomega.2c02117

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