Hybrid N-Acylcysteines as Dual-Acting Matrix Disruptive and Anti-Quorum Sensing Agents Fighting Pseudomonas aeruginosa Biofilms: Design, Synthesis, Molecular Docking Studies, and In Vitro Assays

[Image: see text] Biofilms facilitate the pathogenesis of life-threatening Pseudomonas aeruginosa infections by coating mucosal surfaces or invasive devices and offer protection from antimicrobial therapy and the host immune response, thus increasing mortality rates and financial burden. Herein, new...

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Detalles Bibliográficos
Autores principales: Abo-Dya, Nader E., Agha, Khalid A., Abbas, Hisham A., Abu-Kull, Mansour E., Alahmdi, Mohammed Issa, Osman, Nermine A.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202021/
https://www.ncbi.nlm.nih.gov/pubmed/35721927
http://dx.doi.org/10.1021/acsomega.2c01667

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