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Toward the Total Synthesis of Alpkinidine: Synthesis of Haloquinone CE Ring System Synthons and Attempted Nucleophilic Bisannulation

[Image: see text] Model chemistry involving the bisannulation of 2,3-dichloro-1,4-naphthoquinone with the ester enolate derived from ethyl o-nitrophenylacetic acid, which rapid assembled the ABCD ring system of a pentacyclic pyrroloacridine, has been applied to the attempted synthesis of the marine...

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Detalles Bibliográficos
Autores principales:	Buccini, Marco, Tham, Louisa, Dhoro, Francis, Skelton, Brian W., Williams, Craig M., Piggott, Matthew J.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	American Chemical Society 2022
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202046/ https://www.ncbi.nlm.nih.gov/pubmed/35721899 http://dx.doi.org/10.1021/acsomega.2c02116

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