Calcium-dependent cytosolic phospholipase A(2) activation is implicated in neuroinflammation and oxidative stress associated with ApoE4

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BACKGROUND: Apolipoprotein E4 (APOE4) is associated with a greater response to neuroinflammation and the risk of developing late-onset Alzheimer’s disease (AD), but the mechanisms for this association are not clear. The activation of calcium-dependent cytosolic phospholipase A(2) (cPLA2) is involved...

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Detalles Bibliográficos
Autores principales: Wang, Shaowei, Li, Boyang, Solomon, Victoria, Fonteh, Alfred, Rapoport, Stanley I., Bennett, David A., Arvanitakis, Zoe, Chui, Helena C., Sullivan, Patrick M., Yassine, Hussein N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: BioMed Central 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202185/
https://www.ncbi.nlm.nih.gov/pubmed/35705959
http://dx.doi.org/10.1186/s13024-022-00549-5
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