Cargando…
Empagliflozin attenuates cardiac microvascular ischemia/reperfusion injury through improving mitochondrial homeostasis
BACKGROUND: Empagliflozin has been reported to protect endothelial cell function, regardless of diabetes status. However, the role of empagliflozin in microvascular protection during myocardial ischemia reperfusion injury (I/R) has not been fully understood. METHODS: Electron microscopy, western blo...
Autores principales: | Zou, Rongjun, Shi, Wanting, Qiu, Junxiong, Zhou, Na, Du, Na, Zhou, Hao, Chen, Xinxin, Ma, Li |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
BioMed Central
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202214/ https://www.ncbi.nlm.nih.gov/pubmed/35705980 http://dx.doi.org/10.1186/s12933-022-01532-6 |
Ejemplares similares
-
SGLT2 inhibitor dapagliflozin reduces endothelial dysfunction and microvascular damage during cardiac ischemia/reperfusion injury through normalizing the XO-SERCA2-CaMKII-coffilin pathways
por: Ma, Li, et al.
Publicado: (2022) -
Empagliflozin attenuates cardiac microvascular ischemia/reperfusion through activating the AMPKα1/ULK1/FUNDC1/mitophagy pathway
por: Cai, Chen, et al.
Publicado: (2022) -
SERCA Overexpression Improves Mitochondrial Quality Control and Attenuates Cardiac Microvascular Ischemia-Reperfusion Injury
por: Tan, Ying, et al.
Publicado: (2020) -
Pathological Roles of Mitochondrial Oxidative Stress and Mitochondrial Dynamics in Cardiac Microvascular Ischemia/Reperfusion Injury
por: Zhou, Hao, et al.
Publicado: (2020) -
Ndufs1 Deficiency Aggravates the Mitochondrial Membrane Potential Dysfunction in Pressure Overload-Induced Myocardial Hypertrophy
por: Zou, Rongjun, et al.
Publicado: (2021)