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PPAR-α Agonist Fenofibrate Ameliorates Sjögren Syndrome–Like Dacryoadenitis by Modulating Th1/Th17 and Treg Cell Responses in NOD Mice

PURPOSE: To investigate the effects and mechanisms of fenofibrate, a synthetic ligand of peroxisome proliferator-activated receptor α (PPAR-α), on autoimmune dacryoadenitis in a mouse model of Sjögren syndrome (SS) dry eye. METHODS: Male nonobese diabetic (NOD) mice were fed chow with or without 0.0...

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Detalles Bibliográficos
Autores principales:	Guo, Xingyi, Dang, Weiyu, Li, Na, Wang, Ying, Sun, Deming, Nian, Hong, Wei, Ruihua
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	The Association for Research in Vision and Ophthalmology 2022
Materias:	Immunology and Microbiology
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202336/ https://www.ncbi.nlm.nih.gov/pubmed/35687344 http://dx.doi.org/10.1167/iovs.63.6.12

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