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Divergence in Dimerization and Activity of Primate APOBEC3C

The APOBEC3 (A3) family of single-stranded DNA cytidine deaminases are host restriction factors that inhibit lentiviruses, such as HIV-1, in the absence of the Vif protein that causes their degradation. Deamination of cytidine in HIV-1 (−)DNA forms uracil that causes inactivating mutations when urac...

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Detalles Bibliográficos
Autores principales:	Gaba, Amit, Hix, Mark A., Suhail, Sana, Flath, Ben, Boysan, Brock, Williams, Danielle R., Pelletier, Tomas, Emerman, Michael, Morcos, Faruck, Cisneros, G. Andrés, Chelico, Linda
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	2021
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202443/ https://www.ncbi.nlm.nih.gov/pubmed/34666043 http://dx.doi.org/10.1016/j.jmb.2021.167306

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