Clickable Cisplatin Derivatives as Versatile Tools to Probe the DNA Damage Response to Chemotherapy

Cisplatin induces DNA crosslinks that are highly cytotoxic. Hence, platinum complexes are frequently used in the treatment of a broad range of cancers. Efficiency of cisplatin treatment is limited by the tumor-specific DNA damage response to the generated lesions. We reasoned that better tools to in...

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Detalles Bibliográficos
Autores principales: Moretton, Amandine, Slyskova, Jana, Simaan, Marwan E., Arasa-Verge, Emili A., Meyenberg, Mathilde, Cerrón-Infantes, D. Alonso, Unterlass, Miriam M., Loizou, Joanna I.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Frontiers Media S.A. 2022
Materias:
Oncology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202558/
https://www.ncbi.nlm.nih.gov/pubmed/35719993
http://dx.doi.org/10.3389/fonc.2022.874201

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202558/
https://www.ncbi.nlm.nih.gov/pubmed/35719993
http://dx.doi.org/10.3389/fonc.2022.874201

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