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Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles

[Image: see text] Metabolism is a challenging subject for bioscience students due to the intrinsic complexity of the metabolic network, as well as that of the overlapping mechanisms of metabolic regulation. Collaborative learning based on a problem-based learning approach can help students to succes...

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Autores principales: Medina, Miguel Ángel, García-Ponce, Ángel Luis, Blanco-López, Ángel, Quesada, Ana R., Urdiales, José Luis, Fajardo, Ignacio, Suárez, Fernanda, Alonso-Carrión, Francisco José
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Chemical Society and Division of Chemical Education, Inc. 2022
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202563/
https://www.ncbi.nlm.nih.gov/pubmed/35722632
http://dx.doi.org/10.1021/acs.jchemed.1c01038
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author Medina, Miguel Ángel
García-Ponce, Ángel Luis
Blanco-López, Ángel
Quesada, Ana R.
Urdiales, José Luis
Fajardo, Ignacio
Suárez, Fernanda
Alonso-Carrión, Francisco José
author_facet Medina, Miguel Ángel
García-Ponce, Ángel Luis
Blanco-López, Ángel
Quesada, Ana R.
Urdiales, José Luis
Fajardo, Ignacio
Suárez, Fernanda
Alonso-Carrión, Francisco José
author_sort Medina, Miguel Ángel
collection PubMed
description [Image: see text] Metabolism is a challenging subject for bioscience students due to the intrinsic complexity of the metabolic network, as well as that of the overlapping mechanisms of metabolic regulation. Collaborative learning based on a problem-based learning approach can help students to successfully learn and understand metabolism. In the present article, we propose a selection of exercises, problems, and cases aimed to focus students’ attention on the scientific work made by Sir Hans Krebs and his collaborators to elucidate four main metabolic cycles, as well as on the study of these cycles, their regulation, and their metabolic integration. The objectives, the tools, and the implementation of this proposal are described, and the results obtained during its first implementation with volunteer students enrolled in two courses on metabolic regulation at our university are presented and discussed. These volunteer students signed a learning contract and were randomly distributed in small groups (3–4 students each). Application of this collaborative learning activity to our classrooms has been very satisfactory, as evidenced by an improvement in the volunteers’ academic performance and a very positive perception by most of them, who declared to be “very satisfied” or “satisfied” with their experience and felt that they had learned more.
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spelling pubmed-92025632022-06-17 Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles Medina, Miguel Ángel García-Ponce, Ángel Luis Blanco-López, Ángel Quesada, Ana R. Urdiales, José Luis Fajardo, Ignacio Suárez, Fernanda Alonso-Carrión, Francisco José J Chem Educ [Image: see text] Metabolism is a challenging subject for bioscience students due to the intrinsic complexity of the metabolic network, as well as that of the overlapping mechanisms of metabolic regulation. Collaborative learning based on a problem-based learning approach can help students to successfully learn and understand metabolism. In the present article, we propose a selection of exercises, problems, and cases aimed to focus students’ attention on the scientific work made by Sir Hans Krebs and his collaborators to elucidate four main metabolic cycles, as well as on the study of these cycles, their regulation, and their metabolic integration. The objectives, the tools, and the implementation of this proposal are described, and the results obtained during its first implementation with volunteer students enrolled in two courses on metabolic regulation at our university are presented and discussed. These volunteer students signed a learning contract and were randomly distributed in small groups (3–4 students each). Application of this collaborative learning activity to our classrooms has been very satisfactory, as evidenced by an improvement in the volunteers’ academic performance and a very positive perception by most of them, who declared to be “very satisfied” or “satisfied” with their experience and felt that they had learned more. American Chemical Society and Division of Chemical Education, Inc. 2022-05-25 2022-06-14 /pmc/articles/PMC9202563/ /pubmed/35722632 http://dx.doi.org/10.1021/acs.jchemed.1c01038 Text en © 2022 The Authors. Published by American Chemical Society and Division of Chemical Education, Inc. https://creativecommons.org/licenses/by/4.0/Permits the broadest form of re-use including for commercial purposes, provided that author attribution and integrity are maintained (https://creativecommons.org/licenses/by/4.0/).
spellingShingle Medina, Miguel Ángel
García-Ponce, Ángel Luis
Blanco-López, Ángel
Quesada, Ana R.
Urdiales, José Luis
Fajardo, Ignacio
Suárez, Fernanda
Alonso-Carrión, Francisco José
Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles
title Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles
title_full Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles
title_fullStr Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles
title_full_unstemmed Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles
title_short Turning around Cycles: An Approach Based on Selected Problems/Cases to Stimulate Collaborative Learning about Krebs and His Four Metabolic Cycles
title_sort turning around cycles: an approach based on selected problems/cases to stimulate collaborative learning about krebs and his four metabolic cycles
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202563/
https://www.ncbi.nlm.nih.gov/pubmed/35722632
http://dx.doi.org/10.1021/acs.jchemed.1c01038
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