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Extracellular N(6)-isopentenyladenosine (i(6)A) addition induces cotranscriptional i(6)A incorporation into ribosomal RNAs
N(6)-isopentenyladenosine (i(6)A), a modified adenosine monomer, is known to induce cell death upon its addition to the culture medium. However, the molecular fate of extracellularly added i(6)A has yet to be identified. Here we show that i(6)A addition to cell culture medium results in i(6)A incorp...
Autores principales: | Yakita, Maya, Chujo, Takeshi, Wei, Fan-Yan, Hirayama, Mayumi, Kato, Koji, Takahashi, Nozomu, Naganuma, Kenta, Nagata, Masashi, Kawahara, Kenta, Nakayama, Hideki, Tomizawa, Kazuhito |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Cold Spring Harbor Laboratory Press
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202588/ https://www.ncbi.nlm.nih.gov/pubmed/35414588 http://dx.doi.org/10.1261/rna.079176.122 |
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