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Genetically Determined Reproductive Aging and Coronary Heart Disease: A Bidirectional 2-sample Mendelian Randomization

BACKGROUND: Accelerated reproductive aging, in women indicated by early natural menopause, is associated with increased coronary heart disease (CHD) risk in observational studies. Conversely, an adverse CHD risk profile has been suggested to accelerate menopause. OBJECTIVES: To study the direction a...

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Detalles Bibliográficos
Autores principales:	Dam, Veerle, Onland-Moret, N Charlotte, Burgess, Stephen, Chirlaque, Maria-Dolores, Peters, Sanne A E, Schuit, Ewoud, Tikk, Kaja, Weiderpass, Elisabete, Oliver-Williams, Clare, Wood, Angela M, Tjønneland, Anne, Dahm, Christina C, Overvad, Kim, Boutron-Ruault, Marie-Christine, Schulze, Matthias B, Trichopoulou, Antonia, Ferrari, Pietro, Masala, Giovanna, Krogh, Vittorio, Tumino, Rosario, Matullo, Giuseppe, Panico, Salvatore, Boer, Jolanda M A, Verschuren, W M Monique, Waaseth, Marit, Pérez, Maria José Sánchez, Amiano, Pilar, Imaz, Liher, Moreno-Iribas, Conchi, Melander, Olle, Harlid, Sophia, Nordendahl, Maria, Wennberg, Patrik, Key, Timothy J, Riboli, Elio, Santiuste, Carmen, Kaaks, Rudolf, Katzke, Verena, Langenberg, Claudia, Wareham, Nicholas J, Schunkert, Heribert, Erdmann, Jeanette, Willenborg, Christina, Hengstenberg, Christian, Kleber, Marcus E, Delgado, Graciela, März, Winfried, Kanoni, Stavroula, Dedoussis, George, Deloukas, Panos, Nikpay, Majid, McPherson, Ruth, Scholz, Markus, Teren, Andrej, Butterworth, Adam S, van der Schouw, Yvonne T
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Oxford University Press 2022
Materias:	Online Only Articles
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9202700/ https://www.ncbi.nlm.nih.gov/pubmed/35306566 http://dx.doi.org/10.1210/clinem/dgac171

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