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Single strand gap repair: The presynaptic phase plays a pivotal role in modulating lesion tolerance pathways

During replication, the presence of unrepaired lesions results in the formation of single stranded DNA (ssDNA) gaps that need to be repaired to preserve genome integrity and cell survival. All organisms have evolved two major lesion tolerance pathways to continue replication: Translesion Synthesis (...

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Detalles Bibliográficos
Autores principales:	Laureti, Luisa, Lee, Lara, Philippin, Gaëlle, Kahi, Michel, Pagès, Vincent
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Public Library of Science 2022
Materias:	Research Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203016/ https://www.ncbi.nlm.nih.gov/pubmed/35653392 http://dx.doi.org/10.1371/journal.pgen.1010238

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