Excessive immunosuppression by regulatory T cells antagonizes T cell response to schistosome infection in PD-1-deficient mice

Schistosomiasis is caused by parasitic flatworms known as schistosomes and affects over 200 million people worldwide. Prevention of T cell exhaustion by blockade of PD-1 results in clinical benefits to cancer patients and clearance of viral infections, however it remains largely unknown whether loss...

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Detalles Bibliográficos
Autores principales: Lu, Liaoxun, Li, Tianhan, Feng, Xinyu, Liu, Zhilong, Liu, Yang, Chao, Tianzhu, Gu, Yanrong, Huang, Rong, Zhang, Fanghui, He, Le, Zhou, Binhui, Kong, Eryan, Liu, Zhuangzhuang, Wang, Xugang, Chen, Zhijun, Wang, Hui, Malissen, Marie, Malissen, Bernard, Zhang, Lichen, Liang, Yinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Public Library of Science 2022
Materias:
Research Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203022/
https://www.ncbi.nlm.nih.gov/pubmed/35666747
http://dx.doi.org/10.1371/journal.ppat.1010596

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