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Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience

Aim: To evaluate the clinical course of idiopathic inflammatory myopathy (IIM) patients in COVID-19 pandemic, and to assess the COVID-19 outcomes in infected IIM patients. Materials & methods: In this study, 39 patients were evaluated retrospectively. Myositis disease activity, myositis damage i...

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Autores principales: Apaydin, Hakan, Erden, Abdulsamet, Güven, Serdar C, Armağan, Berkan, Karakaş, Özlem, Özdemir, Bahar, Polat, Bünyamin, Eksin, Mehmet Akif, Omma, Ahmet, Kucuksahin, Orhan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Future Medicine Ltd 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203034/
https://www.ncbi.nlm.nih.gov/pubmed/35747325
http://dx.doi.org/10.2217/fvl-2021-0146
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author Apaydin, Hakan
Erden, Abdulsamet
Güven, Serdar C
Armağan, Berkan
Karakaş, Özlem
Özdemir, Bahar
Polat, Bünyamin
Eksin, Mehmet Akif
Omma, Ahmet
Kucuksahin, Orhan
author_facet Apaydin, Hakan
Erden, Abdulsamet
Güven, Serdar C
Armağan, Berkan
Karakaş, Özlem
Özdemir, Bahar
Polat, Bünyamin
Eksin, Mehmet Akif
Omma, Ahmet
Kucuksahin, Orhan
author_sort Apaydin, Hakan
collection PubMed
description Aim: To evaluate the clinical course of idiopathic inflammatory myopathy (IIM) patients in COVID-19 pandemic, and to assess the COVID-19 outcomes in infected IIM patients. Materials & methods: In this study, 39 patients were evaluated retrospectively. Myositis disease activity, myositis damage index, depression, fatigue, active medical treatment, drug compliance and SARS-CoV-2 PCR test results in COVID-19 pandemic were collected. Results: Fourteen of these patients (35%) were detected to have a positive SARS-CoV-2 PCR test. The demographic and clinical characteristics, active medical treatment, disease activity, depression and fatigue of the patients who had undergone or not SARS-CoV-2 were similar. Conclusion: Our results have shown that although prevalence of COVID-19 seems to be increased in IIM patients under immunosuppressive treatment, hospitalization rates were lower and no intensive care unit admissions or deaths were observed.
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spelling pubmed-92030342022-06-21 Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience Apaydin, Hakan Erden, Abdulsamet Güven, Serdar C Armağan, Berkan Karakaş, Özlem Özdemir, Bahar Polat, Bünyamin Eksin, Mehmet Akif Omma, Ahmet Kucuksahin, Orhan Future Virol Research Article Aim: To evaluate the clinical course of idiopathic inflammatory myopathy (IIM) patients in COVID-19 pandemic, and to assess the COVID-19 outcomes in infected IIM patients. Materials & methods: In this study, 39 patients were evaluated retrospectively. Myositis disease activity, myositis damage index, depression, fatigue, active medical treatment, drug compliance and SARS-CoV-2 PCR test results in COVID-19 pandemic were collected. Results: Fourteen of these patients (35%) were detected to have a positive SARS-CoV-2 PCR test. The demographic and clinical characteristics, active medical treatment, disease activity, depression and fatigue of the patients who had undergone or not SARS-CoV-2 were similar. Conclusion: Our results have shown that although prevalence of COVID-19 seems to be increased in IIM patients under immunosuppressive treatment, hospitalization rates were lower and no intensive care unit admissions or deaths were observed. Future Medicine Ltd 2022-06-15 2022-05 /pmc/articles/PMC9203034/ /pubmed/35747325 http://dx.doi.org/10.2217/fvl-2021-0146 Text en © 2022 Future Medicine Ltd https://creativecommons.org/licenses/by/4.0/This work is licensed under the Creative Commons Attribution 4.0 License (https://creativecommons.org/licenses/by/4.0/)
spellingShingle Research Article
Apaydin, Hakan
Erden, Abdulsamet
Güven, Serdar C
Armağan, Berkan
Karakaş, Özlem
Özdemir, Bahar
Polat, Bünyamin
Eksin, Mehmet Akif
Omma, Ahmet
Kucuksahin, Orhan
Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience
title Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience
title_full Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience
title_fullStr Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience
title_full_unstemmed Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience
title_short Clinical course of idiopathic inflammatory myopathies in COVID-19 pandemic: a single-center experience
title_sort clinical course of idiopathic inflammatory myopathies in covid-19 pandemic: a single-center experience
topic Research Article
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203034/
https://www.ncbi.nlm.nih.gov/pubmed/35747325
http://dx.doi.org/10.2217/fvl-2021-0146
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