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Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins

Two meters of DNA in each of our cells must be protected against many types of damage. Mechanoprotection is increasingly understood to be conferred by the nuclear lamina of intermediate filament proteins, but very different patterns of expression and regulation between different cells and tissues re...

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Detalles Bibliográficos
Autores principales: Wang, Mai, Ivanovska, Irena, Vashisth, Manasvita, Discher, Dennis E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: AIP Publishing LLC 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203124/
https://www.ncbi.nlm.nih.gov/pubmed/35719698
http://dx.doi.org/10.1063/5.0080392