Cargando…

Nuclear mechanoprotection: From tissue atlases as blueprints to distinctive regulation of nuclear lamins

Two meters of DNA in each of our cells must be protected against many types of damage. Mechanoprotection is increasingly understood to be conferred by the nuclear lamina of intermediate filament proteins, but very different patterns of expression and regulation between different cells and tissues re...

Descripción completa

Detalles Bibliográficos
Autores principales:	Wang, Mai, Ivanovska, Irena, Vashisth, Manasvita, Discher, Dennis E.
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	AIP Publishing LLC 2022
Materias:	Reviews
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203124/ https://www.ncbi.nlm.nih.gov/pubmed/35719698 http://dx.doi.org/10.1063/5.0080392

Ejemplares similares

Gaussian curvature dilutes the nuclear lamina, favoring nuclear rupture, especially at high strain rate
por: Pfeifer, Charlotte R., et al.
Publicado: (2022)

Nuclear lamin stiffness is a barrier to 3D migration, but softness can limit survival
por: Harada, Takamasa, et al.
Publicado: (2014)

Nuclear constriction segregates mobile nuclear proteins away from chromatin
por: Irianto, Jerome, et al.
Publicado: (2016)

Cross-linked matrix rigidity and soluble retinoids synergize in nuclear lamina regulation of stem cell differentiation
por: Ivanovska, Irena L., et al.
Publicado: (2017)

Coordinated increase of nuclear tension and lamin-A with matrix stiffness outcompetes lamin-B receptor that favors soft tissue phenotypes
por: Buxboim, Amnon, et al.
Publicado: (2017)

Identification of distinct messenger RNAs for nuclear lamin C and a putative precursor of nuclear lamin A
Publicado: (1984)

Progerin phosphorylation in interphase is lower and less mechanosensitive than lamin-A,C in iPS-derived mesenchymal stem cells
por: Cho, Sangkyun, et al.
Publicado: (2018)

Nuclear lamins: key regulators of nuclear structure and activities
por: Prokocimer, Miron, et al.
Publicado: (2009)

Caveolin-1 modulates intraocular pressure: implications for caveolae mechanoprotection in glaucoma
por: Elliott, Michael H., et al.
Publicado: (2016)

The conserved carboxy-terminal cysteine of nuclear lamins is essential for lamin association with the nuclear envelope
Publicado: (1989)

Nuclear membrane ruptures, cell death, and tissue damage in the setting of nuclear lamin deficiencies
por: Chen, Natalie Y., et al.
Publicado: (2020)

A role for nuclear lamins in nuclear envelope assembly
por: Lopez-Soler, Reynold I., et al.
Publicado: (2001)

Removal of the mechanoprotective influence of the cytoskeleton reveals PIEZO1 is gated by bilayer tension
por: Cox, Charles D., et al.
Publicado: (2016)

Deficiencies in lamin B1 and lamin B2 cause neurodevelopmental defects and distinct nuclear shape abnormalities in neurons
por: Coffinier, Catherine, et al.
Publicado: (2011)

The caveolin–cavin system plays a conserved and critical role in mechanoprotection of skeletal muscle
por: Lo, Harriet P., et al.
Publicado: (2015)

Actomyosin contractility confers mechanoprotection against TNFα-induced disruption of the intervertebral disc
por: Hernandez, Paula A., et al.
Publicado: (2020)

Nuclear Actin and Lamins in Viral Infections
por: Cibulka, Jakub, et al.
Publicado: (2012)

Nuclear lamins: Structure and function in mechanobiology
por: Vahabikashi, Amir, et al.
Publicado: (2022)

Regulation of Nucleotide Excision Repair by Nuclear Lamin B1
por: Butin-Israeli, Veronika, et al.
Publicado: (2013)

Targeted Regulation of Nuclear Lamins by Ubiquitin and Ubiquitin-Like Modifiers
por: Blank, Michael
Publicado: (2020)

ATM Modulates Nuclear Mechanics by Regulating Lamin A Levels
por: Shah, Pragya, et al.
Publicado: (2022)

Nuclear rupture at sites of high curvature compromises retention of DNA repair factors
por: Xia, Yuntao, et al.
Publicado: (2018)

Nuclear F-actin and Lamin A antagonistically modulate nuclear shape
por: Mishra, Sampada, et al.
Publicado: (2022)

Separate roles for chromatin and lamins in nuclear mechanics
por: Stephens, Andrew D., et al.
Publicado: (2017)

Nuclear Lamins: Key Proteins for Embryonic Development
por: Paul, Jasper Chrysolite, et al.
Publicado: (2022)

Dynamic properties of nuclear lamins: lamin B is associated with sites of DNA replication
Publicado: (1994)

Involvement of nuclear lamins in postmitotic reorganization of chromatin as demonstrated by microinjection of lamin antibodies
Publicado: (1986)

Involvement of the Lamin Rod Domain in Heterotypic Lamin Interactions Important for Nuclear Organization
por: Schirmer, Eric C., et al.
Publicado: (2001)

Nuclear lamin phosphorylation: an emerging role in gene regulation and pathogenesis of laminopathies
por: Liu, Sunny Yang, et al.
Publicado: (2020)

Interdependent changes of nuclear lamins, nuclear pore complexes, and ploidy regulate cellular regeneration and stress response in the heart
por: Li, Yao, et al.
Publicado: (2023)

Loss of lamin A function increases chromatin dynamics in the nuclear interior
por: Bronshtein, I., et al.
Publicado: (2015)

Intranuclear HSV-1 DNA ejection induces major mechanical transformations suggesting mechanoprotection of nucleus integrity
por: Evilevitch, Alex, et al.
Publicado: (2022)

Differential Predictive Roles of A- and B-Type Nuclear Lamins in Prostate Cancer Progression
por: Saarinen, Irena, et al.
Publicado: (2015)

Farnesylated Nuclear Proteins Kugelkern and Lamin Dm0 Affect Nuclear Morphology by Directly Interacting with the Nuclear Membrane
por: Polychronidou, Maria, et al.
Publicado: (2010)

The Paradox of Nuclear Lamins in Pathologies: Apparently Controversial Roles Explained by Tissue-Specific Mechanobiology
por: Urciuoli, Enrica, et al.
Publicado: (2022)

Pathway of incorporation of microinjected lamin A into the nuclear envelope
Publicado: (1992)

A lamin-independent pathway for nuclear envelope assembly
Publicado: (1990)

Lamin proteolysis facilitates nuclear events during apoptosis
Publicado: (1996)

The nucleoporin Nup88 is interacting with nuclear lamin A
por: Lussi, Yvonne C., et al.
Publicado: (2011)

Lamins position the nuclear pores and centrosomes by modulating dynein
por: Guo, Yuxuan, et al.
Publicado: (2015)

Cannot write session to /tmp/vufind_sessions/sess_kh1e33q48nivdd3r5dlg9kjs1b