Cargando…

Metabolic Dysfunction in the Regulation of the NLRP3 Inflammasome Activation: A Potential Target for Diabetic Nephropathy

Metabolic dysfunction plays a key role in the development of diabetic nephropathy (DN). However, the exact effects and mechanisms are still unclear. The pyrin domain-containing protein 3 (NLRP3) inflammasome, a member of the nod-like receptor family, is considered a crucial inflammatory regulator an...

Descripción completa

Detalles Bibliográficos
Autores principales:	Zhao, Wenli, Zhou, Le, Novák, Petr, Shi, Xian, Lin, Chuang Biao, Zhu, Xiao, Yin, Kai
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	Hindawi 2022
Materias:	Review Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203236/ https://www.ncbi.nlm.nih.gov/pubmed/35719709 http://dx.doi.org/10.1155/2022/2193768

Ejemplares similares

Curcumin Ameliorates Diabetic Nephropathy by Suppressing NLRP3 Inflammasome Signaling
por: Lu, Miaomiao, et al.
Publicado: (2017)

NLRP3 inflammasome in endothelial dysfunction
por: Bai, Baochen, et al.
Publicado: (2020)

NLRP3 inflammasome: Pathogenic role and potential therapeutic target for IgA nephropathy
por: Tsai, Yu-Ling, et al.
Publicado: (2017)

The Role of NLRP3 Inflammasome in IgA Nephropathy
por: Wu, Xiaofang, et al.
Publicado: (2022)

The Role of the NLRP3 Inflammasome in Mediating Glomerular and Tubular Injury in Diabetic Nephropathy
por: Williams, B. M., et al.
Publicado: (2022)

Nlrp3-inflammasome activation in non-myeloid-derived cells aggravates diabetic nephropathy
por: Shahzad, Khurrum, et al.
Publicado: (2015)

Fisetin Attenuates Diabetic Nephropathy-Induced Podocyte Injury by Inhibiting NLRP3 Inflammasome
por: Dong, Wenmin, et al.
Publicado: (2022)

The NLRP3–inflammasome as a sensor of organelle dysfunction
por: Seoane, Paula I., et al.
Publicado: (2020)

Shikonin Ameliorates LPS-Induced Cardiac Dysfunction by SIRT1-Dependent Inhibition of NLRP3 Inflammasome
por: Guo, Tao, et al.
Publicado: (2020)

NLRP3 Inflammasome in Metabolic-Associated Kidney Diseases: An Update
por: Xiong, Wei, et al.
Publicado: (2021)

The Role of NLRP3 Inflammasome in Diabetic Cardiomyopathy and Its Therapeutic Implications
por: Ding, Kai, et al.
Publicado: (2022)

NLRP3 inflammasome and lipid metabolism analysis based on UPLC-Q-TOF-MS in gouty nephropathy
por: Zhang, Yan-Zi, et al.
Publicado: (2019)

NLRP3 Inflammasome at the Interface of Inflammation, Endothelial Dysfunction, and Type 2 Diabetes
por: Gora, Ilona M., et al.
Publicado: (2021)

Relevance of the pyroptosis-related inflammasome drug targets in the Chuanxiong to improve diabetic nephropathy
por: Li, ChangYan, et al.
Publicado: (2022)

Stabilization of endogenous Nrf2 by minocycline protects against Nlrp3-inflammasome induced diabetic nephropathy
por: Shahzad, Khurrum, et al.
Publicado: (2016)

Sweet Taste Receptors Mediated ROS-NLRP3 Inflammasome Signaling Activation: Implications for Diabetic Nephropathy
por: Zhou, Luping, et al.
Publicado: (2018)

Berberine protects diabetic nephropathy by suppressing epithelial-to-mesenchymal transition involving the inactivation of the NLRP3 inflammasome
por: Ma, Zejun, et al.
Publicado: (2022)

Targeting the NLRP3 Inflammasome in Glaucoma
por: Coyle, Sophie, et al.
Publicado: (2021)

Role of NLRP3 inflammasome in diabetes and COVID-19 role of NLRP3 inflammasome in the pathogenesis and treatment of COVID-19 and diabetes NLRP3 inflammasome in diabetes and COVID-19 intervention
por: Zhang, Jiayu, et al.
Publicado: (2023)

NLRP3 Inflammasome: A Potential Alternative Therapy Target for Atherosclerosis
por: Liu, Yang, et al.
Publicado: (2020)

Inflammation triggered by the NLRP3 inflammasome is a critical driver of diabetic bladder dysfunction
por: Hughes, Francis M., et al.
Publicado: (2022)

NLRP3 inflammasome as a potential treatment in ischemic stroke concomitant with diabetes
por: Hong, Pu, et al.
Publicado: (2019)

Interleukin-22 ameliorated renal injury and fibrosis in diabetic nephropathy through inhibition of NLRP3 inflammasome activation
por: Wang, Shaofei, et al.
Publicado: (2017)

Astragaloside IV ameliorates diabetic nephropathy in db/db mice by inhibiting NLRP3 inflammasome-mediated inflammation
por: Feng, Hui, et al.
Publicado: (2021)

Sacubitril/Valsartan Improves Progression of Early Diabetic Nephropathy in Rats Through Inhibition of NLRP3 Inflammasome Pathway
por: Pan, Yan, et al.
Publicado: (2022)

A small molecule inhibitor MCC950 ameliorates kidney injury in diabetic nephropathy by inhibiting NLRP3 inflammasome activation
por: Zhang, CongXiao, et al.
Publicado: (2019)

The NLRP3 inflammasome: an emerging therapeutic target for chronic pain
por: Chen, Ruixiang, et al.
Publicado: (2021)

Modulatory Mechanisms of the NLRP3 Inflammasomes in Diabetes
por: Ding, Sujuan, et al.
Publicado: (2019)

Targeting the NLRP3 Inflammasome via BTK
por: Weber, Alexander N. R.
Publicado: (2021)

Mitochondrial dysfunction in hearing loss: Oxidative stress, autophagy and NLRP3 inflammasome
por: Li, Peipei, et al.
Publicado: (2023)

NLRP3 Inflammasome: A Potential Target in Isoflurane Pretreatment Alleviates Stroke-Induced Retinal Injury in Diabetes
por: Lin, Hong-Bin, et al.
Publicado: (2021)

Blockade of Autophagy Prevents the Progression of Hyperuricemic Nephropathy Through Inhibiting NLRP3 Inflammasome-Mediated Pyroptosis
por: Hu, Yan, et al.
Publicado: (2022)

Kakonein restores diabetes‐induced endothelial junction dysfunction via promoting autophagy‐mediated NLRP3 inflammasome degradation
por: Lian, Dawei, et al.
Publicado: (2021)

Sinapine Thiocyanate Ameliorates Vascular Endothelial Dysfunction in Hypertension by Inhibiting Activation of the NLRP3 Inflammasome
por: Liu, Yang, et al.
Publicado: (2021)

NLRP3 Inflammasome and Mineralocorticoid Receptors Are Associated with Vascular Dysfunction in Type 2 Diabetes Mellitus
por: Ferreira, Nathanne Santos, et al.
Publicado: (2019)

The NLRP6 inflammasome
por: Zheng, Danping, et al.
Publicado: (2020)

DsbA-L Ameliorates Renal Injury Through the AMPK/NLRP3 Inflammasome Signaling Pathway in Diabetic Nephropathy
por: Yang, Ming, et al.
Publicado: (2021)

TLR9 regulates NLRP3 inflammasome activation via the NF-kB signaling pathway in diabetic nephropathy
por: Shen, Jinfeng, et al.
Publicado: (2022)

The NLRP3 Inflammasome: Metabolic Regulation and Contribution to Inflammaging
por: Meyers, Allison K., et al.
Publicado: (2020)

Dapagliflozin protects against dilated cardiomyopathy progression by targeting NLRP3 inflammasome activation
por: Hu, Jiaxin, et al.
Publicado: (2023)

Cannot write session to /tmp/vufind_sessions/sess_d0ekjp7cec50bhfu8rrqb7csgl