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The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis

Leptospirosis is a zoonotic disease that the pathogen can be transmitted to humans through the excretions of infected animals. In the Republic of Korea, the Livestock Manure Control Act was enforced in September 2007 to improve underground water hygiene. The objective of this study was to evaluate t...

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Autores principales: RYU, S., LAU, C. L., CHUN, B. C.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Cambridge University Press 2017
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203346/
https://www.ncbi.nlm.nih.gov/pubmed/28215193
http://dx.doi.org/10.1017/S0950268817000218
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author RYU, S.
LAU, C. L.
CHUN, B. C.
author_facet RYU, S.
LAU, C. L.
CHUN, B. C.
author_sort RYU, S.
collection PubMed
description Leptospirosis is a zoonotic disease that the pathogen can be transmitted to humans through the excretions of infected animals. In the Republic of Korea, the Livestock Manure Control Act was enforced in September 2007 to improve underground water hygiene. The objective of this study was to evaluate the impact of Livestock Manure Control Policy on the incidence and the trend of human leptospirosis. An interrupted time series analysis using the monthly incidence of leptospirosis was conducted based on data derived from the Korean National Surveillance System between January 1999 and January 2015. We used a Spearman correlation method to compare the level of leptospirosis incidence decrease between the metropolitan cities and rural provinces. The annual incidence of leptospirosis in South Korea decreased by 33% after policy enforcement of the policy. A significant change in the slope of human leptospirosis cases was observed after the policy enforcement (β = −0·09, P < 0·001). Moreover, we detected a clear association between the size of the rice paddy fields and the decrease in leptospirosis incidence in provinces (r = 0·817, P = 0·01). This study shows that the Livestock Manure Control Policy had significantly reduced human leptospirosis incidence in the Republic of Korea, in particular, in rural regions.
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spelling pubmed-92033462022-06-29 The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis RYU, S. LAU, C. L. CHUN, B. C. Epidemiol Infect Original Papers Leptospirosis is a zoonotic disease that the pathogen can be transmitted to humans through the excretions of infected animals. In the Republic of Korea, the Livestock Manure Control Act was enforced in September 2007 to improve underground water hygiene. The objective of this study was to evaluate the impact of Livestock Manure Control Policy on the incidence and the trend of human leptospirosis. An interrupted time series analysis using the monthly incidence of leptospirosis was conducted based on data derived from the Korean National Surveillance System between January 1999 and January 2015. We used a Spearman correlation method to compare the level of leptospirosis incidence decrease between the metropolitan cities and rural provinces. The annual incidence of leptospirosis in South Korea decreased by 33% after policy enforcement of the policy. A significant change in the slope of human leptospirosis cases was observed after the policy enforcement (β = −0·09, P < 0·001). Moreover, we detected a clear association between the size of the rice paddy fields and the decrease in leptospirosis incidence in provinces (r = 0·817, P = 0·01). This study shows that the Livestock Manure Control Policy had significantly reduced human leptospirosis incidence in the Republic of Korea, in particular, in rural regions. Cambridge University Press 2017-05 2017-02-20 /pmc/articles/PMC9203346/ /pubmed/28215193 http://dx.doi.org/10.1017/S0950268817000218 Text en © Cambridge University Press 2017 https://creativecommons.org/licenses/by/4.0/This is an Open Access article, distributed under the terms of the Creative Commons Attribution licence (http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) ), which permits unrestricted re-use, distribution, and reproduction in any medium, provided the original work is properly cited.
spellingShingle Original Papers
RYU, S.
LAU, C. L.
CHUN, B. C.
The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis
title The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis
title_full The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis
title_fullStr The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis
title_full_unstemmed The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis
title_short The impact of Livestock Manure Control Policy on human leptospirosis in Republic of Korea using interrupted time series analysis
title_sort impact of livestock manure control policy on human leptospirosis in republic of korea using interrupted time series analysis
topic Original Papers
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203346/
https://www.ncbi.nlm.nih.gov/pubmed/28215193
http://dx.doi.org/10.1017/S0950268817000218
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