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Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes
PURPOSE: To evaluate the outcome of pneumatic vitreolysis (PVL) for vitreomacular traction (VMT) with or without full thickness macular hole (MH) < 400 µm. METHODS: Forty-seven eyes of 47 patients were included who had undergone PVL for VMT with or without MH. Main outcome measures were release o...
Autores principales: | , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
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Springer Berlin Heidelberg
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203395/ https://www.ncbi.nlm.nih.gov/pubmed/35122133 http://dx.doi.org/10.1007/s00417-022-05568-y |
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author | Baumann, Carmen Sabatino, Francesco Zheng, Yalin Johannigmann-Malek, Navid Maier, Mathias Kaye, Stephen B. Patton, Niall |
author_facet | Baumann, Carmen Sabatino, Francesco Zheng, Yalin Johannigmann-Malek, Navid Maier, Mathias Kaye, Stephen B. Patton, Niall |
author_sort | Baumann, Carmen |
collection | PubMed |
description | PURPOSE: To evaluate the outcome of pneumatic vitreolysis (PVL) for vitreomacular traction (VMT) with or without full thickness macular hole (MH) < 400 µm. METHODS: Forty-seven eyes of 47 patients were included who had undergone PVL for VMT with or without MH. Main outcome measures were release of VMT, MH closure, best-corrected visual acuity (BCVA) and adverse events. RESULTS: Thirty-three patients had isolated VMT and 14 patients VMT with a MH. Four weeks after PVL, the overall VMT release rate was 35/47 (74.5%): 25/37 (67.6%) in phakic and 10/10 (100%) in pseudophakic eyes (p = 0.03). Four of 14 MH (28.6%) were closed. Twenty-two of 47 (46.8%) eyes required a subsequent PPV: 12/33 (36.4%) in the VMT only group and 10/14 (71.4%) in the VMT with MH group. Mean BCVA improved from 0.48 (± 0.24) to 0.34 (± 0.23) logMAR at 6 months in patients with VMT alone (p < 0.001), and from 0.57 (± 0.27) to 0.41 (± 0.28) logMAR in patients with VMT and MH (p = 0.008). Adverse events included new formation of a large MH in 4/33 (12.1%) eyes, failure of MH closure in 10/14 (71.4%) eyes, progression of mean minimum linear diameter (MLD) MH size from baseline 139 (± 67) to 396 (± 130) µm (p < 0.001) and development of a retinal detachment in 4/47 (8.5%) eyes. CONCLUSION: While PVL leads to a high VMT release rate particularly in pseudophakic eyes, it is associated with a relatively high incidence of MH formation, MH size progression and retinal detachment. |
format | Online Article Text |
id | pubmed-9203395 |
institution | National Center for Biotechnology Information |
language | English |
publishDate | 2022 |
publisher | Springer Berlin Heidelberg |
record_format | MEDLINE/PubMed |
spelling | pubmed-92033952022-06-18 Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes Baumann, Carmen Sabatino, Francesco Zheng, Yalin Johannigmann-Malek, Navid Maier, Mathias Kaye, Stephen B. Patton, Niall Graefes Arch Clin Exp Ophthalmol Retinal Disorders PURPOSE: To evaluate the outcome of pneumatic vitreolysis (PVL) for vitreomacular traction (VMT) with or without full thickness macular hole (MH) < 400 µm. METHODS: Forty-seven eyes of 47 patients were included who had undergone PVL for VMT with or without MH. Main outcome measures were release of VMT, MH closure, best-corrected visual acuity (BCVA) and adverse events. RESULTS: Thirty-three patients had isolated VMT and 14 patients VMT with a MH. Four weeks after PVL, the overall VMT release rate was 35/47 (74.5%): 25/37 (67.6%) in phakic and 10/10 (100%) in pseudophakic eyes (p = 0.03). Four of 14 MH (28.6%) were closed. Twenty-two of 47 (46.8%) eyes required a subsequent PPV: 12/33 (36.4%) in the VMT only group and 10/14 (71.4%) in the VMT with MH group. Mean BCVA improved from 0.48 (± 0.24) to 0.34 (± 0.23) logMAR at 6 months in patients with VMT alone (p < 0.001), and from 0.57 (± 0.27) to 0.41 (± 0.28) logMAR in patients with VMT and MH (p = 0.008). Adverse events included new formation of a large MH in 4/33 (12.1%) eyes, failure of MH closure in 10/14 (71.4%) eyes, progression of mean minimum linear diameter (MLD) MH size from baseline 139 (± 67) to 396 (± 130) µm (p < 0.001) and development of a retinal detachment in 4/47 (8.5%) eyes. CONCLUSION: While PVL leads to a high VMT release rate particularly in pseudophakic eyes, it is associated with a relatively high incidence of MH formation, MH size progression and retinal detachment. Springer Berlin Heidelberg 2022-02-05 2022 /pmc/articles/PMC9203395/ /pubmed/35122133 http://dx.doi.org/10.1007/s00417-022-05568-y Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open AccessThis article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons licence, and indicate if changes were made. The images or other third party material in this article are included in the article's Creative Commons licence, unless indicated otherwise in a credit line to the material. If material is not included in the article's Creative Commons licence and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this licence, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) . |
spellingShingle | Retinal Disorders Baumann, Carmen Sabatino, Francesco Zheng, Yalin Johannigmann-Malek, Navid Maier, Mathias Kaye, Stephen B. Patton, Niall Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes |
title | Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes |
title_full | Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes |
title_fullStr | Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes |
title_full_unstemmed | Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes |
title_short | Anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes |
title_sort | anatomical and functional outcomes of pneumatic vitreolysis for treatment of vitreomacular traction with and without macular holes |
topic | Retinal Disorders |
url | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203395/ https://www.ncbi.nlm.nih.gov/pubmed/35122133 http://dx.doi.org/10.1007/s00417-022-05568-y |
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