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Recurrent exon-deleting activating mutations in AHR act as drivers of urinary tract cancer
Bladder cancer has a high recurrence rate and low survival of advanced stage patients. Few genetic drivers of bladder cancer have thus far been identified. We performed in-depth structural variant analysis on whole-genome sequencing data of 206 metastasized urinary tract cancers. In ~ 10% of the pat...
Autores principales: | Vlaar, Judith M., Borgman, Anouska, Kalkhoven, Eric, Westland, Denise, Besselink, Nicolle, Shale, Charles, Faltas, Bishoy M., Priestley, Peter, Kuijk, Ewart, Cuppen, Edwin |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
Nature Publishing Group UK
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203531/ https://www.ncbi.nlm.nih.gov/pubmed/35710704 http://dx.doi.org/10.1038/s41598-022-14256-0 |
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