Unmixing for ultra-high-plex fluorescence imaging

Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications...

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Detalles Bibliográficos
Autores principales: Enninful, Archibald, Baysoy, Alev, Fan, Rong
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Comment
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203536/
https://www.ncbi.nlm.nih.gov/pubmed/35710800
http://dx.doi.org/10.1038/s41467-022-31110-z
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author Enninful, Archibald
Baysoy, Alev
Fan, Rong
author_facet Enninful, Archibald
Baysoy, Alev
Fan, Rong
author_sort Enninful, Archibald
collection PubMed
description Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy.
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spelling pubmed-92035362022-06-18 Unmixing for ultra-high-plex fluorescence imaging Enninful, Archibald Baysoy, Alev Fan, Rong Nat Commun Comment Writing in Nature communications, Seo and collaborators presented PICASSO as a method to achieve 15-color imaging of spatially overlapping proteins using no reference emission spectra in a single staining and imaging round. This accessible tool has the potential to be applied to diverse applications within the spatial biology field without neglecting accuracy. Nature Publishing Group UK 2022-06-16 /pmc/articles/PMC9203536/ /pubmed/35710800 http://dx.doi.org/10.1038/s41467-022-31110-z Text en © The Author(s) 2022 https://creativecommons.org/licenses/by/4.0/Open Access This article is licensed under a Creative Commons Attribution 4.0 International License, which permits use, sharing, adaptation, distribution and reproduction in any medium or format, as long as you give appropriate credit to the original author(s) and the source, provide a link to the Creative Commons license, and indicate if changes were made. The images or other third party material in this article are included in the article’s Creative Commons license, unless indicated otherwise in a credit line to the material. If material is not included in the article’s Creative Commons license and your intended use is not permitted by statutory regulation or exceeds the permitted use, you will need to obtain permission directly from the copyright holder. To view a copy of this license, visit http://creativecommons.org/licenses/by/4.0/ (https://creativecommons.org/licenses/by/4.0/) .
spellingShingle Comment
Enninful, Archibald
Baysoy, Alev
Fan, Rong
Unmixing for ultra-high-plex fluorescence imaging
title Unmixing for ultra-high-plex fluorescence imaging
title_full Unmixing for ultra-high-plex fluorescence imaging
title_fullStr Unmixing for ultra-high-plex fluorescence imaging
title_full_unstemmed Unmixing for ultra-high-plex fluorescence imaging
title_short Unmixing for ultra-high-plex fluorescence imaging
title_sort unmixing for ultra-high-plex fluorescence imaging
topic Comment
url https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203536/
https://www.ncbi.nlm.nih.gov/pubmed/35710800
http://dx.doi.org/10.1038/s41467-022-31110-z
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