T-cell trans-synaptic vesicles are distinct and carry greater effector content than constitutive extracellular vesicles

The immunological synapse is a molecular hub that facilitates the delivery of three activation signals, namely antigen, costimulation/corepression and cytokines, from antigen-presenting cells (APC) to T cells. T cells release a fourth class of signaling entities, trans-synaptic vesicles (tSV), to me...

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Detalles Bibliográficos
Autores principales: Céspedes, Pablo F., Jainarayanan, Ashwin, Fernández-Messina, Lola, Valvo, Salvatore, Saliba, David G., Kurz, Elke, Kvalvaag, Audun, Chen, Lina, Ganskow, Charity, Colin-York, Huw, Fritzsche, Marco, Peng, Yanchun, Dong, Tao, Johnson, Errin, Siller-Farfán, Jesús A., Dushek, Omer, Sezgin, Erdinc, Peacock, Ben, Law, Alice, Aubert, Dimitri, Engledow, Simon, Attar, Moustafa, Hester, Svenja, Fischer, Roman, Sánchez-Madrid, Francisco, Dustin, Michael L.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: Nature Publishing Group UK 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9203538/
https://www.ncbi.nlm.nih.gov/pubmed/35710644
http://dx.doi.org/10.1038/s41467-022-31160-3

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